Description

Palmitoyl-(Methyl-D3)-Lactosylceramide is a deuterated isotopologue of a key sphingolipid, specifically labeled on the methyl group of the palmitoyl moiety. This compound is critically important for advanced research and development in lipidomics and metabolic pathway tracing, offering enhanced analytical precision. It is primarily needed by pharmaceutical R&D teams, academic research institutions, and diagnostic developers working on biomarker discovery, drug metabolism studies (ADME), and stable isotope labeling techniques.

Application

• Biomarker Research & Discovery: Used as an internal standard in mass spectrometry for the accurate quantification of native lactosylceramides in biological samples.
• Drug Metabolism & Pharmacokinetics (DMPK): Employed in ADME studies to trace the metabolic fate of sphingolipids and related drug candidates.
• Lipidomics & Metabolomics: Serves as a critical reference standard for profiling and validating complex lipid species in cellular and plasma samples.
• Stable Isotope Labeling Studies: Facilitates research into sphingolipid biosynthesis, turnover, and catabolic pathways using tracer methodologies.
• Diagnostic Assay Development: Utilized in the calibration and validation of LC-MS/MS assays for clinical research targeting lipid disorders.
• Cell Signaling Research: Applied in studies investigating the role of glycosphingolipids in cell membrane structure, signaling, and disease mechanisms.

Basic Information

Product Name	Palmitoyl-(Methyl-D3)-Lactosylceramide
CAS No.	2097249-92-6
Molecular Formula	C51H92D3NO13
Molecular Weight	~927.3 g/mol
Synonyms	D3-Palmitoyl Lactosylceramide; Lactosylceramide (d3); N-[(1S,2R,3E)-2-Hydroxy-1-(hydroxymethyl)-3-heptadecen-1-yl]-O-β-D-galactopyranosyl-(1→4)-β-D-glucopyranonosyl-(1↔1)-N-(hexadecanoyl-d3)-sphingosine; Deuterated Lactosylceramide; Lactosylceramide-d3; β-D-Galactosyl-(1→4)-β-D-glucosylceramide (d3); N-Palmitoyl-(methyl-d3)-D-erythro-sphingosyl-β-D-lactoside
EINECS	Contact for details

Quality Control

Our Palmitoyl-(Methyl-D3)-Lactosylceramide is manufactured under strict quality systems to ensure the highest isotopic and chemical purity for research applications. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing results from NMR, HPLC, and mass spectrometry. We adhere to relevant standards for high-purity reference materials to guarantee batch-to-batch consistency and reliability for your critical research.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). For long-term storage, keep desiccated under an inert atmosphere. Allow the vial to warm to room temperature in a desiccator before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (NMR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95%
Isotopic Purity (D-content)	≥ 98 atom % D
Water Content (KF)	≤ 2.0 %
Solubility	Soluble in chloroform/methanol mixtures, DMSO

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.