Description

5-Methyl-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1,3-thiazole is a high-value, heterocyclic boronic ester derivative that serves as a critical building block in modern synthetic chemistry. Its primary value lies in its role as a versatile coupling partner in Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly in the development of novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for compounds containing the 1,3-thiazole pharmacophore.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides that require specific thiazole-based structures.
• Material Science: Employed in the development of organic electronic materials, such as organic light-emitting diodes (OLEDs) and semiconductors, where precise molecular engineering is crucial.
• Chemical Research & Development: Serves as a fundamental reagent in academic and industrial R&D labs for exploring new synthetic pathways and creating compound libraries via cross-coupling chemistry.
• Ligand Synthesis: Can be utilized to create novel ligands for catalysis or metal-organic frameworks (MOFs).

Basic Information

Product Name	5-Methyl-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1,3-thiazole
CAS No.	2096996-97-1
Molecular Formula	C10H16BNO2S
Molecular Weight	225.12 g/mol
Synonyms	5-Methyl-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)thiazole; 2-(5-Methylthiazol-2-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 5-Methyl-2-thiazoleboronic acid pinacol ester; (5-Methylthiazol-2-yl)boronic acid pinacol ester; 2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-5-methyl-1,3-thiazole; Pinacol (5-methylthiazol-2-yl)boronate; CAS 2096996-97-1
EINECS	Contact for details

Quality Control

Every batch of 5-Methyl-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1,3-thiazole is manufactured and tested under strict quality management systems. We ensure compliance with high-purity standards suitable for research and commercial synthesis. Comprehensive analytical testing, including HPLC, NMR, and GC, is performed to verify identity, purity, and consistency. Certificates of Analysis (COA) are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent moisture absorption and degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.