Description

2-[3-(Trifluoromethyl)Phenoxy]Pyridine-5-Boronic Acid is a high-value boronic acid derivative and a key synthetic intermediate in modern organic chemistry. Its molecular structure, featuring a pyridine ring linked to a trifluoromethylphenoxy group, makes it an essential building block for constructing complex molecules with tailored properties. This compound is primarily utilized by researchers and process chemists in the pharmaceutical and agrochemical industries for the development of new active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A crucial building block in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, particularly in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides, leveraging the stability and reactivity of the boronic acid functional group.
• Material Science Research: Serves as a precursor for creating organic electronic materials, such as ligands for metal-organic frameworks (MOFs) or components for organic light-emitting diodes (OLEDs).
• Chemical Biology Probes: Employed in the synthesis of molecular probes and sensors for studying biological processes and enzyme activity.
• Custom Synthesis & Contract Manufacturing: A key starting material for custom synthesis services catering to R&D and pilot-scale production needs.

Basic Information

Product Name	2-[3-(Trifluoromethyl)Phenoxy]Pyridine-5-Boronic Acid
CAS No.	2096332-23-7
Molecular Formula	C12H9BF3NO3
Molecular Weight	283.01 g/mol
Synonyms	5-Borono-2-[3-(trifluoromethyl)phenoxy]pyridine; [5-(3-Trifluoromethylphenoxy)pyridin-2-yl]boronic acid; 2-(3-Trifluoromethylphenoxy)pyridine-5-boronic acid; 2-(α,α,α-Trifluoro-m-tolyloxy)pyridine-5-boronic acid; Pyridine, 5-borono-2-[3-(trifluoromethyl)phenoxy]-; 2096332-23-7; 2-(3-Trifluoromethylphenoxy)-5-pyridineboronic acid
EINECS	Contact for details

Quality Control

Our 2-[3-(Trifluoromethyl)Phenoxy]Pyridine-5-Boronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and process chemistry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.