Description

1-[(5E)-5,6-Dideoxy-6-(Diethoxyphosphinyl)-2-o-Methyl-β-D-Ribo-Hex-5-Enofuranosyl]Uracil is a sophisticated nucleoside analog intermediate of significant interest in advanced pharmaceutical research and development. This compound is specifically engineered to serve as a key building block in the synthesis of novel antiviral and anticancer therapeutics, offering researchers a precise tool for probing biological pathways. It is primarily utilized by R&D scientists and process chemists in the pharmaceutical, biotechnology, and fine chemical sectors working on nucleoside-based drug discovery programs.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel nucleoside analog drugs targeting viral infections and oncology.
• Antiviral Drug Research: Used in the development of next-generation antiviral agents, particularly against DNA viruses.
• Anticancer Agent Development: Serves as a scaffold for creating compounds that interfere with cancer cell DNA/RNA synthesis.
• Biochemical Probe: Employed in enzymatic studies to investigate the mechanisms of nucleoside-metabolizing enzymes.
• Process Chemistry & Scale-Up: A valuable intermediate for optimizing synthetic routes and scaling up production of active pharmaceutical ingredients (APIs).
• Academic & Institutional Research: Used in university and research institute labs for fundamental studies in medicinal chemistry and chemical biology.

Basic Information

Product Name	1-[(5E)-5,6-Dideoxy-6-(Diethoxyphosphinyl)-2-o-Methyl-β-D-Ribo-Hex-5-Enofuranosyl]Uracil
CAS No.	2095417-05-1
Molecular Formula	C16H25N2O9P
Molecular Weight	420.35 g/mol
Synonyms	2'-O-Methyluridine 5'-(diethyl phosphate); 5'-(Diethyl phosphate)-2'-O-methyluridine; 2'-O-Methyl-5'-O-(diethoxyphosphoryl)uridine; Uridine, 2'-O-methyl-, 5'-(diethyl phosphate); 1-[(5E)-5,6-Dideoxy-6-(diethoxyphosphinyl)-2-O-methyl-β-D-ribo-hex-5-enofuranosyl]uracil; Phosphorylated 2'-O-Methyluridine derivative; Nucleoside phosphonate intermediate
EINECS	Contact for details

Quality Control

Our production of 1-[(5E)-5,6-Dideoxy-6-(Diethoxyphosphinyl)-2-o-Methyl-β-D-Ribo-Hex-5-Enofuranosyl]Uracil adheres to stringent quality protocols suitable for research and development applications. Each batch is characterized using advanced analytical techniques including HPLC, NMR, and mass spectrometry to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all critical specifications are provided to support your regulatory and quality documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment. For long-term storage, consider desiccants or an inert atmosphere to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.