Description

Methyl 7-Bromothieno[2,3-C]Pyridine-2-Carboxylate is a high-value brominated heterocyclic building block essential for modern pharmaceutical and agrochemical research. This compound matters as a key synthetic intermediate, enabling the construction of complex molecular architectures through versatile cross-coupling and functionalization reactions. It is primarily needed by medicinal chemists and process development scientists in the pharmaceutical industry for the discovery and synthesis of novel active ingredients, particularly in oncology and CNS therapeutic areas.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel small-molecule drug candidates, especially kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used in the development of new active ingredients for crop protection, leveraging its unique fused thienopyridine scaffold.
• Material Science: Serves as a building block for advanced organic electronic materials, such as organic semiconductors and light-emitting materials.
• Chemical Biology: Employed as a molecular probe or a tagged fragment in fragment-based drug discovery (FBDD) and chemical proteomics studies.
• Cross-Coupling Reactions: The bromine atom makes it an excellent substrate for Suzuki, Stille, and Buchwald-Hartwig amination reactions to introduce complex substituents.
• Academic & Contract Research: A valuable reagent for universities and CROs (Contract Research Organizations) exploring new synthetic methodologies and heterocyclic chemistry.

Basic Information

Product Name	Methyl 7-Bromothieno[2,3-C]Pyridine-2-Carboxylate
CAS No.	2092325-80-7
Molecular Formula	C10H6BrNO2S
Molecular Weight	287.13 g/mol
Synonyms	7-Bromothieno[2,3-c]pyridine-2-carboxylic acid methyl ester; Methyl 7-bromothieno[2,3-c]pyridine-2-carboxylate; 7-Bromo-thieno[2,3-c]pyridine-2-carboxylic acid methyl ester; Thieno[2,3-c]pyridine-2-carboxylic acid, 7-bromo-, methyl ester; 2092325-80-7
EINECS	Contact for details

Quality Control

Our production of Methyl 7-Bromothieno[2,3-C]Pyridine-2-Carboxylate adheres to stringent internal quality standards to ensure batch-to-batch consistency and high purity for research and development applications. Each lot is characterized by advanced analytical techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your regulatory and quality documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep the container sealed to protect this light-sensitive material from prolonged exposure.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.