Description

5-Bromo-3-(Difluoromethyl)-1H-Indol-4-Ol is a high-value, multi-functional indole derivative serving as a critical synthetic intermediate in advanced organic chemistry. Its unique bromo- and difluoromethyl-substituted indole scaffold makes it an essential building block for constructing complex molecules with tailored biological and physical properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly for oncology, CNS, and anti-inflammatory targets, leveraging its halogenated indole core.
• Agrochemical Research: Used in developing next-generation herbicides, fungicides, and plant growth regulators where the difluoromethyl group enhances metabolic stability and bioavailability.
• Material Science: Serves as a monomer or functional unit in the creation of specialty polymers, organic semiconductors, and advanced dyes.
• Chemical Biology & Proteomics: Employed as a molecular probe or a tag in activity-based protein profiling (ABPP) and bioconjugation strategies.
• Academic & Contract Research: Fundamental building block for methodological development in organic synthesis, fluorination chemistry, and heterocyclic compound libraries.

Basic Information

Product Name	5-Bromo-3-(Difluoromethyl)-1H-Indol-4-Ol
CAS No.	2091581-91-6
Molecular Formula	C9H6BrF2NO
Molecular Weight	262.05 g/mol
Synonyms	4-Hydroxy-5-bromo-3-(difluoromethyl)-1H-indole; 5-Bromo-3-(difluoromethyl)-1H-indol-4-ol; 1H-Indol-4-ol, 5-bromo-3-(difluoromethyl)-; 2091581-91-6
EINECS	Contact for details

Quality Control

Every batch of 5-Bromo-3-(Difluoromethyl)-1H-Indol-4-Ol is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure identity, purity, and consistency meet the exacting standards required for research and scale-up applications. Certificates of Analysis (COA) with detailed HPLC, NMR, and MS results are available for all shipments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere for long-term storage.

Specification

Item	Specification
Appearance	Off-white to light brown crystalline powder
Identification (HPLC)	Retention time corresponds to reference standard
Identification (NMR)	Spectrum consistent with structure
Purity (HPLC)	≥ 97.0% (Area Percent)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.