Description

6-Bromo-3,3-Dimethyl-3,4-Dihydroisoquinolin-1(2H)-One is a high-value, synthetically versatile brominated isoquinolinone derivative that serves as a critical building block in advanced organic synthesis. Its molecular structure, featuring a reactive bromine substituent and a constrained heterocyclic framework, makes it an indispensable intermediate for constructing complex pharmacophores and functional materials. This compound is primarily sought after by research institutions and industrial R&D teams in the pharmaceutical, agrochemical, and specialty chemical sectors for developing new active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potential drug candidates, particularly for central nervous system (CNS) and oncology targets.
• Agrochemical Research: Used to develop novel herbicides, fungicides, and insecticides with new modes of action.
• Material Science: Building block for creating organic semiconductors, light-emitting materials, and advanced polymers.
• Chemical Biology: Employed as a molecular probe or scaffold in medicinal chemistry for structure-activity relationship (SAR) studies.
• Academic & Contract Research: Essential reagent for methodological development and novel synthetic route exploration in university and CRO laboratories.
• Custom Synthesis: Serves as a starting material for the contract manufacturing of bespoke fine chemicals and advanced intermediates.

Basic Information

Product Name	6-Bromo-3,3-Dimethyl-3,4-Dihydroisoquinolin-1(2H)-One
CAS No.	2091182-77-1
Molecular Formula	C11H12BrNO
Molecular Weight	254.13 g/mol
Synonyms	6-Bromo-3,3-dimethyl-1,2,3,4-tetrahydroisoquinolin-1-one; 6-Bromo-3,3-dimethyl-3,4-dihydro-1H-isoquinolin-1-one; 1(2H)-Isoquinolinone, 6-bromo-3,3-dimethyl-3,4-dihydro-; 2091182-77-1; 6-Bromo-3,3-dimethyl-1,2,3,4-tetrahydroisoquinoline-1-one
EINECS	Contact for details

Quality Control

Every batch of 6-Bromo-3,3-Dimethyl-3,4-Dihydroisoquinolin-1(2H)-One is manufactured and tested under a strict quality management system to ensure consistency and purity for research and development applications. Our products undergo rigorous analytical characterization using techniques such as HPLC, GC, NMR, and MS. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your regulatory and quality documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). The compound may be light-sensitive; prolonged exposure to light should be avoided. Keep container tightly sealed when not in use to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.