Description

Methyl 4-(Hydroxymethyl)Bicyclo[2.1.1]Hexane-1-Carboxylate is a high-purity, advanced pharmaceutical intermediate featuring a unique strained bicyclic scaffold. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in medicinal chemistry research and development. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key synthon for the development of new drug candidates, especially those targeting central nervous system (CNS) disorders and inflammatory diseases.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to explore novel bioactive compounds.
• Agrochemical Synthesis: Serves as a precursor for developing new generation pesticides and herbicides with unique modes of action.
• Material Science: Potential monomer or cross-linker for creating polymers with specific thermal or mechanical properties derived from its rigid bicyclic structure.
• Academic Research: Employed in organic synthesis methodologies and catalysis studies due to its strained ring system.
• Custom Synthesis & Contract Manufacturing: A starting material for the bespoke production of complex target molecules for clients.

Basic Information

Product Name	Methyl 4-(Hydroxymethyl)Bicyclo[2.1.1]Hexane-1-Carboxylate
CAS No.	2090676-64-3
Molecular Formula	C10H14O3
Molecular Weight	182.22 g/mol
Synonyms	Methyl 4-(hydroxymethyl)bicyclo[2.1.1]hexane-1-carboxylate; 1-Bicyclo[2.1.1]hexanecarboxylic acid, 4-(hydroxymethyl)-, methyl ester; Methyl 4-(hydroxymethyl)bicyclo[2.1.1]hexane-1-carboxylate; Bicyclo[2.1.1]hexane-1-carboxylic acid, 4-(hydroxymethyl)-, methyl ester
EINECS	Contact for details

Quality Control

Our production of Methyl 4-(Hydroxymethyl)Bicyclo[2.1.1]Hexane-1-Carboxylate adheres to stringent quality management protocols. Every batch is analyzed using advanced techniques like HPLC, GC, and NMR to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality system is designed to support cGMP compliance for pharmaceutical applications, ensuring traceability and reliability for our global partners.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Recommended storage temperature is between 2°C and 8°C for long-term stability. The material is moisture-sensitive; keep the container tightly sealed under an inert atmosphere if specified. Keep away from heat and open flame.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Any single unknown impurity	≤ 0.5%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.