Description

4-Chlorothiophen-2-Amine Hydrochloride is a high-purity organic building block, specifically a halogenated thiophene derivative, essential for advanced chemical synthesis. Its primary value lies in serving as a critical intermediate for constructing complex heterocyclic compounds in pharmaceutical and agrochemical research. This compound is particularly needed by R&D chemists and process development scientists working on active pharmaceutical ingredients (APIs), crop protection agents, and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting various therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, leveraging the thiophene scaffold for bioactivity.
• Material Science Research: Serves as a precursor for the development of organic electronic materials, such as conductive polymers and semiconductors.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes and labeled compounds for biochemical and diagnostic applications.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing specialized fine chemicals.
• Academic & Industrial R&D: Fundamental reagent in university and corporate research laboratories for exploring new synthetic methodologies and heterocyclic chemistry.

Basic Information

Product Name	4-Chlorothiophen-2-Amine Hydrochloride
CAS No.	2089333-85-5
Molecular Formula	C4H5Cl2NS
Molecular Weight	178.06 g/mol
Synonyms	2-Amino-4-chlorothiophene Hydrochloride; 4-Chloro-2-aminothiophene Hydrochloride; 4-Chloro-2-thiophenamine Hydrochloride; 4-Chlorothiophen-2-ylamine Hydrochloride; 2-Thiophenamine, 4-chloro-, hydrochloride; 4-Chloro-2-thienylamine Hydrochloride
EINECS	Contact for details

Quality Control

Our 4-Chlorothiophen-2-Amine Hydrochloride is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity, suitable for demanding research and development applications. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing key parameters such as identity, purity, and impurity profiles. While produced to meet general reagent-grade standards, specifications can be aligned with specific project requirements for advanced synthetic work.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.