Description

tert-Butyl (7-Bromoisoquinolin-3-Yl)Carbamate is a high-purity, advanced pharmaceutical intermediate featuring a brominated isoquinoline core protected by a Boc (tert-butoxycarbonyl) group. This compound is critical for medicinal chemistry research and development, serving as a versatile building block for the synthesis of novel drug candidates. It is primarily utilized by R&D scientists and process chemists in the pharmaceutical, biotechnology, and agrochemical industries to construct complex molecules targeting various therapeutic areas.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs) and preclinical drug candidates.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new therapeutic agents.
• Protease Inhibitor Development: The isoquinoline scaffold is relevant in the development of inhibitors for various enzymes.
• Kinase Inhibitor Synthesis: Serves as a precursor in the creation of compounds targeting kinase pathways in oncology and inflammatory diseases.
• Agrochemical Research: Intermediate for developing new crop protection agents and pesticides.
• Chemical Biology Probes: Used to create labeled or tagged molecules for studying biological processes and target engagement.

Basic Information

Product Name	tert-Butyl (7-Bromoisoquinolin-3-Yl)Carbamate
CAS No.	2089301-09-5
Molecular Formula	C₁₄H₁₅BrN₂O₂
Molecular Weight	323.19 g/mol
Synonyms	7-Bromo-3-isoquinolinyl tert-butylcarbamate; tert-Butyl 7-bromoisoquinolin-3-ylcarbamate; Boc-7-Bromo-3-aminoisoquinoline; 7-Bromo-3-[(tert-butoxycarbonyl)amino]isoquinoline; 3-[(tert-Butoxycarbonyl)amino]-7-bromoisoquinoline; 7-Bromoisoquinolin-3-amine, N-Boc protected; (7-Bromoisoquinolin-3-yl)carbamic acid tert-butyl ester
EINECS	Contact for details

Quality Control

Our tert-Butyl (7-Bromoisoquinolin-3-Yl)Carbamate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support development and commercial projects with material suitable for research use and can discuss scalable synthesis under cGMP guidelines for advanced clinical stages.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.