Description

1H-Indazol-5-Ol, 3-Iodo-1-(Tetrahydro-2H-Pyran-2-Yl)- is a high-value iodinated indazole derivative featuring a tetrahydropyran (THP) protecting group. This compound is a critical pharmaceutical intermediate and organic building block for advanced chemical synthesis. It is primarily sought by R&D and production teams in the pharmaceutical, agrochemical, and advanced material science sectors for developing novel active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of targeted kinase inhibitors and other small-molecule drug candidates.
• Organic Synthesis Building Block: Utilized in cross-coupling reactions (e.g., Suzuki, Sonogashira) to construct complex heterocyclic systems.
• Agrochemical Research: Serves as a scaffold for developing new herbicides and fungicides with novel modes of action.
• Chemical Biology Probe Development: Used to create molecular probes for studying enzyme function and cellular signaling pathways.
• Material Science: Potential monomer or precursor for specialty polymers and organic electronic materials.

Basic Information

Product Name	1H-Indazol-5-Ol, 3-Iodo-1-(Tetrahydro-2H-Pyran-2-Yl)-
CAS No.	2066567-78-8
Molecular Formula	C12H13IN2O2
Molecular Weight	344.15 g/mol
Synonyms	3-Iodo-1-(tetrahydro-2H-pyran-2-yl)-1H-indazol-5-ol; 3-Iodo-1-(tetrahydropyran-2-yl)-1H-indazol-5-ol; 1-(Oxan-2-yl)-3-iodo-1H-indazol-5-ol; 5-Hydroxy-3-iodo-1-(tetrahydro-2H-pyran-2-yl)-1H-indazole; 3-Iodo-1-THP-1H-indazol-5-ol; THP-protected 3-iodoindazol-5-ol; 2066567-78-8
EINECS	Contact for details

Quality Control

Our production of 1H-Indazol-5-Ol, 3-Iodo-1-(Tetrahydro-2H-Pyran-2-Yl)- adheres to stringent in-process controls to ensure batch-to-batch consistency and high purity. All material is characterized by modern analytical techniques including HPLC, NMR, and MS. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment. We support development and cGMP-grade production needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound is light-sensitive (store away from light). For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	Off-white to light yellow solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.