Description

8-Bromo-1,2,3,4-Tetrahydro-2,6-Naphthyridine Dihydrochloride is a high-purity, advanced pharmaceutical intermediate with the CAS registry number 2055840-70-3. This compound is critical for medicinal chemistry research and development, serving as a key building block in the synthesis of novel therapeutic agents. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical industries.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of active pharmaceutical ingredients (APIs) targeting various disease pathways.
• Medicinal Chemistry Research: Used in hit-to-lead and lead optimization campaigns for constructing complex heterocyclic scaffolds with potential biological activity.
• Chemical Biology Probes: Serves as a starting material for developing tool compounds and probes to study enzyme function and cellular processes.
• Process Development & Scale-Up: Employed in route scouting and optimization for the commercial-scale manufacturing of candidate drugs.
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations supporting drug discovery and development pipelines.
• Academic Research: Utilized in university and institutional labs for fundamental studies in organic synthesis and drug discovery methodologies.

Basic Information

Product Name	8-Bromo-1,2,3,4-Tetrahydro-2,6-Naphthyridine Dihydrochloride
CAS No.	2055840-70-3
Molecular Formula	C8H11BrCl2N2
Molecular Weight	286.00 g/mol
Synonyms	8-Bromo-1,2,3,4-tetrahydro-2,6-naphthyridine dihydrochloride; 8-Bromo-1,2,3,4-tetrahydro-2,6-naphthyridine hydrochloride (1:2); 2,6-Naphthyridine, 8-bromo-1,2,3,4-tetrahydro-, dihydrochloride; 2055840-70-3; 8-Br-THN dihydrochloride
EINECS	Contact for details

Quality Control

Our 8-Bromo-1,2,3,4-Tetrahydro-2,6-Naphthyridine Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We support development and commercial projects with material produced under current Good Manufacturing Practice (cGMP) standards as required.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label. This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere or in a controlled, low-humidity environment to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.