Description

1H-Indazole,3-Fluoro-1-(Tetrahydro-2H-Pyran-2-Yl)-5-(4,4,4-Trifluoro-1-Butyn-1-Yl)- is a high-value, fluorinated indazole derivative designed for advanced pharmaceutical and agrochemical research. This compound serves as a critical building block for medicinal chemistry, enabling the synthesis of novel molecules with targeted biological activity. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and crop protection industries seeking to develop new active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly in oncology, CNS disorders, and anti-inflammatory therapies.
• Agrochemical Research: Used as a precursor in the synthesis of novel herbicides, fungicides, and insecticides with enhanced efficacy and environmental profiles.
• Chemical Biology Probe: Serves as a scaffold for creating molecular probes to study enzyme function and biological pathways.
• Material Science: Potential application in the development of advanced organic electronic materials due to its unique fluorinated structure.
• Process Chemistry: Employed in route scouting and optimization for the scalable production of complex active pharmaceutical ingredients (APIs).
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations supporting global drug discovery and development pipelines.

Basic Information

Product Name	1H-Indazole,3-Fluoro-1-(Tetrahydro-2H-Pyran-2-Yl)-5-(4,4,4-Trifluoro-1-Butyn-1-Yl)-
CAS No.	2052136-98-6
Molecular Formula	C16H14F4N2O
Molecular Weight	326.29 g/mol
Synonyms	3-Fluoro-1-(tetrahydro-2H-pyran-2-yl)-5-(4,4,4-trifluorobut-1-yn-1-yl)-1H-indazole; 3-Fluoro-1-(tetrahydropyran-2-yl)-5-(4,4,4-trifluorobut-1-ynyl)-1H-indazole; 1-(Oxan-2-yl)-3-fluoro-5-(4,4,4-trifluorobut-1-yn-1-yl)-1H-indazole; 2052136-98-6; THP-protected fluorinated indazole alkyne; Fluorinated indazole building block
EINECS	Contact for details

Quality Control

Our 1H-Indazole,3-Fluoro-1-(Tetrahydro-2H-Pyran-2-Yl)-5-(4,4,4-Trifluoro-1-Butyn-1-Yl)- is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity, essential for sensitive research applications. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a cool, dry, and well-ventilated area. Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.