Description

2-Butenamide, N,n-Dimethyl-4-[[2-[[5-[(1Z)-4,4,4-Trifluoro-1-(3-Fluoro-1H-Indazol-5-Yl)-2-Phenyl-1-Buten-1-Yl]-2-Pyridinyl]Oxy]Ethyl]Amino]-, (2E)- is a sophisticated, high-purity organic compound designed for advanced research and development applications. This molecule is of significant interest due to its complex structure, which incorporates indazole and pyridine moieties, making it a valuable intermediate in pharmaceutical discovery. It is primarily targeted at medicinal chemists and process development scientists working in the life sciences sector. This compound is supplied to meet the stringent requirements of modern drug discovery programs.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for targeted therapies.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new drug candidates.
• Biochemical Tool Compound: Potential use as a probe or inhibitor in biochemical assays to study specific biological pathways.
• Process Chemistry Development: Employed in scaling up synthetic routes and optimizing manufacturing processes for complex molecules.
• Contract Research & Development (CRO/CMO): Supplied to organizations specializing in outsourced drug discovery and development services.
• Academic Research: Utilized in university and institutional labs for cutting-edge research in organic synthesis and chemical biology.

Basic Information

Product Name	2-Butenamide, N,n-Dimethyl-4-[[2-[[5-[(1Z)-4,4,4-Trifluoro-1-(3-Fluoro-1H-Indazol-5-Yl)-2-Phenyl-1-Buten-1-Yl]-2-Pyridinyl]Oxy]Ethyl]Amino]-, (2E)-
CAS No.	2052130-80-8
Molecular Formula	C₃₀H₂₈F₄N₄O₂
Molecular Weight	552.57 g/mol
Synonyms	N,N-Dimethyl-4-((2-((5-((Z)-4,4,4-Trifluoro-1-(3-fluoro-1H-indazol-5-yl)-2-phenylbut-1-en-1-yl)pyridin-2-yl)oxy)ethyl)amino)but-2-enamide; (2E)-N,N-Dimethyl-4-[2-[[5-[(1Z)-4,4,4-trifluoro-1-(3-fluoro-1H-indazol-5-yl)-2-phenylbut-1-en-1-yl]pyridin-2-yl]oxy]ethylamino]but-2-enamide; 2052130-80-8; Advanced Pharmaceutical Intermediate; Indazole-Pyridine Based Compound.
EINECS	Contact for details

Quality Control

Our 2-Butenamide, N,n-Dimethyl-4-[[2-[[5-[(1Z)-4,4,4-Trifluoro-1-(3-Fluoro-1H-Indazol-5-Yl)-2-Phenyl-1-Buten-1-Yl]-2-Pyridinyl]Oxy]Ethyl]Amino]-, (2E)- is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical characterization using techniques including HPLC, NMR, and MS to ensure identity, purity, and batch-to-batch consistency. Certificates of Analysis (COA) detailing all specifications are provided and available upon request to support your regulatory and research documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry, well-ventilated area. This compound is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive); handle and store under inert atmosphere if specified for your grade.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.