Description

Ethyl 5-Bromo-2-(2,2,2-trifluoroacetamido)thiophene-3-carboxylate is a high-value, multi-functional heterocyclic building block designed for advanced synthetic chemistry. This compound matters because it provides a versatile scaffold for constructing complex molecules, particularly in the development of novel pharmaceuticals and agrochemicals. It is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries who require reliable, high-purity intermediates for their synthesis pipelines.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those containing the thiophene heterocycle for therapeutic applications.
• Agrochemical Research: Serves as a building block for developing new herbicides, fungicides, and insecticides with potentially enhanced efficacy.
• Material Science: Used in the research and development of organic electronic materials, such as semiconductors and conductive polymers.
• Chemical Biology: Employed as a probe or linker in the design of molecules for studying biological pathways and target engagement.
• Custom Synthesis: A critical starting material for contract research organizations (CROs) and CDMOs performing bespoke synthesis for client projects.
• Academic Research: Utilized in university and institutional labs for methodological development and exploring new chemical spaces in heterocyclic chemistry.

Basic Information

Product Name	Ethyl 5-Bromo-2-(2,2,2-trifluoroacetamido)thiophene-3-carboxylate
CAS No.	2044706-51-4
Molecular Formula	C9H7BrF3NO3S
Molecular Weight	346.12 g/mol
Synonyms	5-Bromo-2-[(2,2,2-trifluoroacetyl)amino]-3-thiophenecarboxylic acid ethyl ester; Ethyl 5-bromo-2-[(trifluoroacetyl)amino]thiophene-3-carboxylate; 2-Amino-5-bromothiophene-3-carboxylic acid ethyl ester, N-trifluoroacetyl derivative; 5-Bromo-2-(trifluoroacetamido)thiophene-3-carboxylic acid ethyl ester; 2044706-51-4; N-(5-Bromo-3-(ethoxycarbonyl)thiophen-2-yl)-2,2,2-trifluoroacetamide
EINECS	Contact for details

Quality Control

Our Ethyl 5-Bromo-2-(2,2,2-trifluoroacetamido)thiophene-3-carboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliable supply and traceability for critical R&D and production applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound may be light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.