Description

(S)-3-(tert-Butyl)-4-(2,6-Dimethoxy-3,5-Dimethylphenyl)-2,3-Dihydrobenzo[D][1,3]Oxaphosphole CAS NO 2021202-03-7 is a high-purity, chiral organophosphorus compound featuring a unique benzo[d][1,3]oxaphosphole core. This compound is of significant value as a specialized intermediate or ligand in advanced synthetic chemistry, particularly for the development of pharmaceuticals and agrochemicals. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for applications requiring precise stereochemical control.

Application

• Pharmaceutical Intermediate: Key chiral building block for the synthesis of novel active pharmaceutical ingredients (APIs), especially in kinase inhibitor or other targeted therapy research.
• Asymmetric Catalysis Ligand: Potential use as a chiral ligand in transition metal-catalyzed reactions, such as asymmetric hydrogenation or cross-coupling, to induce enantioselectivity.
• Agrochemical Synthesis: Intermediate in the research and development of new, stereochemically-defined pesticides and herbicides.
• Material Science Research: Precursor for novel organic electronic materials or chiral polymers where the phosphole moiety can influence electronic properties.
• Academic & Industrial R&D: A valuable tool compound for methodological studies in organic synthesis and catalysis within university and corporate research laboratories.

Basic Information

Item	Details
Product Name	(S)-3-(tert-Butyl)-4-(2,6-Dimethoxy-3,5-Dimethylphenyl)-2,3-Dihydrobenzo[D][1,3]Oxaphosphole
CAS No.	2021202-03-7
Molecular Formula	C23H29O3P
Molecular Weight	384.45 g/mol
Synonyms	(S)-3-tert-Butyl-4-(2,6-dimethoxy-3,5-dimethylphenyl)-2,3-dihydro-1,3-benzoxaphosphole; (S)-3-(tert-Butyl)-4-(2,6-dimethoxy-3,5-dimethylphenyl)-2,3-dihydrobenzo[d][1,3]oxaphosphole; (S)-3-(tert-Butyl)-4-(2,6-dimethoxy-3,5-dimethylphenyl)-2,3-dihydro-1,3-benzoxaphosphole; Benzoxaphosphole derivative, CAS 2021202-03-7; Chiral benzoxaphosphole ligand; tert-Butyl-dimethoxy-dimethylphenyl-dihydrobenzoxaphosphole
EINECS	Contact for details

Quality Control

Our (S)-3-(tert-Butyl)-4-(2,6-Dimethoxy-3,5-Dimethylphenyl)-2,3-Dihydrobenzo[D][1,3]Oxaphosphole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure high chemical and enantiomeric purity suitable for demanding R&D and scale-up applications. Certificates of Analysis (COA) with detailed specifications are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound is light-sensitive; prolonged exposure to light should be avoided to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.