Description

5-Chloro-6-Nitro-2,3-Dihydro-1H-Indole is a high-purity, advanced pharmaceutical intermediate characterized by its halogenated and nitrated indoline core structure. This compound matters for its critical role as a versatile building block in the synthesis of complex bioactive molecules, particularly in medicinal chemistry research and development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for creating novel drug candidates and specialty chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel small molecule drug candidates, particularly those targeting central nervous system (CNS) disorders and oncology.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to explore new chemical entities.
• Agrochemical Synthesis: Serves as a precursor in the development of new herbicides and pesticides, leveraging its nitro and chloro functional groups.
• Fine Chemical Production: Employed in the multi-step synthesis of complex dyes, pigments, and other specialty organic compounds.
• Academic & Contract Research: Utilized in university and CRO laboratories for methodological development and novel heterocyclic chemistry.

Basic Information

Product Name	5-Chloro-6-Nitro-2,3-Dihydro-1H-Indole
CAS No.	2007919-15-3
Molecular Formula	C8H7ClN2O2
Molecular Weight	198.61 g/mol
Synonyms	5-Chloro-6-nitroindoline; 2,3-Dihydro-5-chloro-6-nitro-1H-indole; 1H-Indole, 5-chloro-2,3-dihydro-6-nitro-; 5-Chloro-6-nitroindoline; 6-Nitro-5-chloro-2,3-dihydro-1H-indole
EINECS	Contact for details

Quality Control

Our 5-Chloro-6-Nitro-2,3-Dihydro-1H-Indole is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical research and development processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be opaque or stored in dark conditions.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Area%)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity	≤ 0.5%
Total Impurities	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.