Description

tert-Butyl 3-Aminoindoline-1-Carboxylate Oxalate is a high-purity, advanced pharmaceutical intermediate of significant commercial and research interest. This compound serves as a critical building block in the synthesis of complex organic molecules, particularly in medicinal chemistry. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of new active pharmaceutical ingredients (APIs) and fine chemicals. Its defined structure and purity are essential for ensuring reproducibility and efficacy in downstream synthetic processes.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders.
• Organic Synthesis Building Block: Used in the construction of complex indoline-based heterocycles and other fused ring systems for research and development.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies and lead optimization programs within drug discovery.
• Fine Chemical Production: Integral in the multi-step synthesis of specialty chemicals and high-value agrochemical intermediates.
• Academic Research: Utilized in universities and R&D labs for methodological development and the study of new synthetic pathways.
• Contract Manufacturing (CMO/CDMO): Supplied to contract organizations for the cGMP production of clinical trial materials and commercial APIs.

Basic Information

Product Name	tert-Butyl 3-Aminoindoline-1-Carboxylate Oxalate
CAS No.	2007909-04-6
Molecular Formula	C13H18N2O2 • C2H2O4
Molecular Weight	Contact for details
Synonyms	1-Boc-3-aminoindoline oxalate; tert-Butyl 3-amino-2,3-dihydro-1H-indole-1-carboxylate oxalate; 3-Aminoindoline-1-carboxylic acid tert-butyl ester oxalate; 1H-Indole-1-carboxylic acid, 3-amino-2,3-dihydro-, 1,1-dimethylethyl ester, ethanedioate; Boc-3-Aminoindoline Oxalate Salt; 3-Amino-N-Boc-indoline oxalic acid salt
EINECS	Contact for details

Quality Control

Our tert-Butyl 3-Aminoindoline-1-Carboxylate Oxalate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our quality commitment aligns with the standards expected for pharmaceutical R&D and cGMP intermediate production.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.