Description

Methyl 1-Boc-3-Bromoindole-4-Carboxylate is a high-purity, advanced pharmaceutical intermediate crucial for modern drug discovery and development. This compound serves as a key building block in the synthesis of complex molecules, particularly in the creation of novel therapeutic agents targeting various diseases. It is primarily utilized by research institutions, pharmaceutical R&D laboratories, and fine chemical manufacturers engaged in the production of active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of complex indole-based drug candidates and active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used extensively in lead optimization and structure-activity relationship (SAR) studies for developing new therapeutic compounds.
• Organic Synthesis Building Block: The protected bromo-indole scaffold is valuable for constructing diverse heterocyclic libraries via cross-coupling reactions like Suzuki or Buchwald-Hartwig amination.
• Agrochemical Development: Serves as an intermediate in the research and synthesis of novel crop protection agents and pesticides.
• Academic & Industrial R&D: Employed in chemical research for methodological development and the exploration of new synthetic pathways.

Basic Information

Product Name	Methyl 1-Boc-3-Bromoindole-4-Carboxylate
CAS No.	2006277-62-7
Molecular Formula	C15H16BrNO4
Molecular Weight	354.20 g/mol
Synonyms	1-Boc-3-Bromo-4-Carbomethoxyindole; Methyl 3-Bromo-1-[(tert-butoxy)carbonyl]-1H-indole-4-carboxylate; 3-Bromo-1-(tert-butoxycarbonyl)indole-4-carboxylic acid methyl ester; tert-Butyl 3-bromo-4-(methoxycarbonyl)-1H-indole-1-carboxylate; 1H-Indole-4-carboxylic acid, 3-bromo-1-[(1,1-dimethylethoxy)carbonyl]-, methyl ester; 2006277-62-7; Boc-3-Br-indole-4-COOMe
EINECS	Contact for details

Quality Control

Our Methyl 1-Boc-3-Bromoindole-4-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, supporting compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container sealed to protect this light-sensitive material from moisture and atmospheric contaminants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.