Description

2-((2S,3S)-3-(tert-Butyl)-4-(2,6-Dimethoxyphenyl)-2,3-Dihydrobenzo[D][1,3]Oxaphosphol-2-Yl)-6-Methoxypyridine is a high-purity, stereochemically defined organophosphorus compound with CAS No. 2003230-67-7. This compound serves as a critical chiral intermediate or ligand in advanced synthetic chemistry, enabling the production of complex molecules with high enantioselectivity. It is primarily required by pharmaceutical R&D and fine chemical synthesis teams developing new active pharmaceutical ingredients (APIs) and specialty chemicals.

Application

• Pharmaceutical Intermediate: Key building block in the asymmetric synthesis of novel drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Chiral Ligand/Precursor: Used in the development of asymmetric catalysts for enantioselective transformations such as hydrogenation, cross-coupling, and C-H activation reactions.
• Agrochemical Research: Intermediate for the synthesis of advanced, stereospecific pesticides and herbicides.
• Material Science: Potential monomer or additive for creating specialized polymers with unique optical or electronic properties.
• Academic & Industrial R&D: A valuable tool compound for methodological development in organic and organometallic chemistry laboratories.

Basic Information

Product Name	2-((2S,3S)-3-(tert-Butyl)-4-(2,6-Dimethoxyphenyl)-2,3-Dihydrobenzo[D][1,3]Oxaphosphol-2-Yl)-6-Methoxypyridine
CAS No.	2003230-67-7
Molecular Formula	C27H30NO4P
Molecular Weight	463.50 g/mol
Synonyms	(2S,3S)-3-(tert-Butyl)-4-(2,6-dimethoxyphenyl)-2-(6-methoxypyridin-2-yl)-2,3-dihydrobenzo[d][1,3]oxaphosphole; 2-[(2S,3S)-3-tert-Butyl-4-(2,6-dimethoxyphenyl)-2,3-dihydro-1,3-benzoxaphosphol-2-yl]-6-methoxypyridine; (2S,3S)-3-tert-Butyl-4-(2,6-dimethoxyphenyl)-2-(6-methoxypyridin-2-yl)-2,3-dihydro-1,3-benzoxaphosphole; CAS 2003230-67-7; Benzoxaphosphole derivative; Chiral benzoxaphosphole ligand; Organophosphorus heterocycle.
EINECS	Contact for details

Quality Control

Our production of 2-((2S,3S)-3-(tert-Butyl)-4-(2,6-Dimethoxyphenyl)-2,3-Dihydrobenzo[D][1,3]Oxaphosphol-2-Yl)-6-Methoxypyridine adheres to stringent GMP-like guidelines to ensure batch-to-batch consistency and high chemical purity. Identity, purity, and stereochemical integrity are confirmed via advanced analytical techniques including HPLC, NMR, and chiral analysis. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is light-sensitive and should be handled under an inert atmosphere when appropriate to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.