Description

6-((tert-Butyldimethylsilyl)Oxy)Benzofuran-3(2H)-One is a protected benzofuranone derivative, a key synthetic intermediate in advanced organic chemistry. Its value lies in the tert-butyldimethylsilyl (TBDMS) protecting group, which shields reactive hydroxyl functionalities during multi-step synthesis, enabling the precise construction of complex molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical sectors developing novel active ingredients.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of potential drug candidates, particularly for compounds with benzofuran or related heterocyclic scaffolds.
• Agrochemical Research: Used in developing new herbicides, fungicides, and insecticides where the protected benzofuranone core is a key structural motif.
• Organic Synthesis Reagent: Serves as a versatile synthon in academic and industrial R&D for constructing complex natural products and specialty chemicals.
• Material Science Precursor: Potential intermediate in the synthesis of organic electronic materials or advanced polymers requiring specific, protected functional groups.
• Process Chemistry: Employed in scale-up and optimization of synthetic routes for commercial production of fine chemicals.

Basic Information

Product Name	6-((tert-Butyldimethylsilyl)Oxy)Benzofuran-3(2H)-One
CAS No.	299912-77-9
Molecular Formula	C₁₄H₂₀O₃Si
Molecular Weight	264.40 g/mol
Synonyms	6-(tert-Butyldimethylsilyloxy)-3(2H)-benzofuranone; 6-OTBDMS Benzofuran-3-one; 6-[(tert-Butyldimethylsilyl)oxy]-2,3-dihydro-1-benzofuran-3-one; 6-Hydroxybenzofuran-3(2H)-one TBDMS ether; 6-TBDMS-O-Benzofuran-3-one; 6-(tert-Butyldimethylsiloxy)benzofuran-3(2H)-one; 6-O-(tert-Butyldimethylsilyl)benzofuran-3-ol
EINECS	Contact for details

Quality Control

Our 6-((tert-Butyldimethylsilyl)Oxy)Benzofuran-3(2H)-One is produced under strict quality management systems to ensure batch-to-batch consistency and high purity for research and development applications. All materials are accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We support our clients with full traceability and documentation to meet the stringent requirements of process development and cGMP environments where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). This compound is moisture-sensitive (hygroscopic) and should be handled under inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.