Description

Methyl 2-Acetyl-3-(2-Chloro-4-Fluorophenyl)Acrylate is a high-value, multi-functional acrylate ester derivative designed for advanced chemical synthesis. This compound serves as a critical pharmaceutical intermediate and a versatile building block in the development of complex organic molecules. It is essential for R&D and production teams in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce specific fluorinated and chlorinated aromatic motifs into their target compounds.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders, anti-inflammatory agents, and kinase inhibitors.
• Agrochemical Synthesis: Building block for developing novel herbicides, fungicides, and insecticides, leveraging the bioactivity of the fluorinated phenyl group.
• Material Science Research: Monomer or cross-linking agent in the development of specialty polymers with tailored optical or electronic properties.
• Organic Synthesis Reagent: Used in Michael addition reactions, cyclization processes, and as a dienophile in Diels-Alder reactions for constructing complex heterocyclic systems.
• Fluorescent Dye & Pigment Intermediate: Serves in the synthesis of advanced fluorophores and functional dyes due to its conjugated acrylate structure.

Basic Information

Item	Detail
Product Name	Methyl 2-Acetyl-3-(2-Chloro-4-Fluorophenyl)Acrylate
CAS No.	298709-35-0
Molecular Formula	C12H10ClFO3
Molecular Weight	256.66 g/mol
Synonyms	Methyl (E)-2-acetyl-3-(2-chloro-4-fluorophenyl)acrylate; Methyl 2-acetyl-3-(2-chloro-4-fluorophenyl)-2-propenoate; 2-Propenoic acid, 2-acetyl-3-(2-chloro-4-fluorophenyl)-, methyl ester; (2E)-2-Acetyl-3-(2-chloro-4-fluorophenyl)acrylic acid methyl ester; Methyl α-acetyl-β-(2-chloro-4-fluorophenyl)acrylate
EINECS	Contact for details

Quality Control

Our Methyl 2-Acetyl-3-(2-Chloro-4-Fluorophenyl)Acrylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and batch-to-batch consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, open flames, and incompatible materials such as strong oxidizing agents and bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.