Description

(S)-5,5',6,6',7,7',8,8'-Octahydro-1,1'-Bi-2-Naphthyl Phosphate is a chiral, sterically hindered phosphate derivative of a hydrogenated binaphthyl scaffold, serving as a sophisticated ligand and catalyst precursor in advanced organic synthesis. Its value lies in enabling highly enantioselective transformations, which are critical for producing single-isomer pharmaceuticals and fine chemicals. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries who require precise stereochemical control.

Application

• Asymmetric Catalysis: As a chiral ligand for transition metals (e.g., Rh, Ru, Pd) in enantioselective hydrogenation, C-C bond formation, and other catalytic reactions.
• Pharmaceutical Intermediate Synthesis: A key building block or directing agent in the multi-step synthesis of chiral active pharmaceutical ingredients (APIs).
• Chiral Resolution Agent: Used to separate enantiomers of racemic mixtures through the formation of diastereomeric complexes.
• Material Science Research: A precursor for developing chiral polymers, liquid crystals, or advanced functional materials with specific optical properties.
• Agrochemical Development: Employed in the research and synthesis of enantiomerically pure herbicides, fungicides, and plant growth regulators.
• Academic & Industrial R&D: A valuable tool for methodological development in organic chemistry and process optimization studies.

Basic Information

Product Name	(S)-5,5',6,6',7,7',8,8'-Octahydro-1,1'-Bi-2-Naphthyl Phosphate
CAS No.	297752-25-1
Molecular Formula	C20H21O4P
Molecular Weight	356.35 g/mol
Synonyms	(S)-H8-BINOL Phosphate; (S)-Octahydrobinaphthyl Phosphate; (S)-5,5',6,6',7,7',8,8'-Octahydro-1,1'-binaphthalen-2,2'-diyl Hydrogen Phosphate; (S)-H8-BINAPO?; (S)-Perhydro-BINOL Phosphate; (S)-1,1'-Bi-2-naphthol, 5,5',6,6',7,7',8,8'-octahydro-, 2,2'-phosphate; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our (S)-5,5',6,6',7,7',8,8'-Octahydro-1,1'-Bi-2-Naphthyl Phosphate is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for research and process chemistry. Certificates of Analysis (COA) detailing identity, purity, and enantiomeric excess are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under an inert atmosphere when appropriate to minimize degradation. Keep away from strong bases and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.