Description

4A(2H)-Phenanthrenemethanol, 1,3,4,10A-Tetrahydro-7-Hydroxy-1,1-Dimethyl-8-(1-Methylethyl)-, (4Ar,10As)- is a complex, stereochemically defined phenanthrene derivative of significant interest in advanced organic synthesis. This compound matters as a sophisticated chemical building block for pharmaceutical research and the development of novel active ingredients. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for creating new molecular entities with potential biological activity.

Application

• Pharmaceutical Intermediate: Serves as a key chiral precursor in the synthesis of novel drug candidates, particularly for central nervous system (CNS) or anti-inflammatory targets.
• Agrochemical Research: Used in developing new active ingredients for crop protection, leveraging its complex polycyclic structure.
• Advanced Material Synthesis: Acts as a monomer or functional unit in the creation of specialty polymers and organic electronic materials.
• Chemical Biology Probe Development: Utilized as a scaffold for creating molecular probes to study biological pathways and protein interactions.
• Academic & Institutional Research: Employed in universities and research institutes for methodological studies in stereoselective synthesis and natural product analog development.
• Process Chemistry & Scale-Up: Provides a model compound for optimizing catalytic asymmetric reactions and purification processes on a pilot scale.

Basic Information

Product Name	4A(2H)-Phenanthrenemethanol, 1,3,4,10A-Tetrahydro-7-Hydroxy-1,1-Dimethyl-8-(1-Methylethyl)-, (4Ar,10As)-
CAS No.	297179-19-2
Molecular Formula	C20H28O2
Molecular Weight	300.44 g/mol
Synonyms	(4aR,10aS)-1,3,4,10a-Tetrahydro-7-hydroxy-1,1-dimethyl-8-(propan-2-yl)-4aH-phenanthren-2-ol; (4aR,10aS)-7-Hydroxy-1,1-dimethyl-8-isopropyl-1,3,4,10a-tetrahydro-4aH-phenanthren-2-ol; 4aH-Phenanthren-2-ol, 1,3,4,10a-tetrahydro-7-hydroxy-1,1-dimethyl-8-(1-methylethyl)-, (4aR,10aS)-; 4a(2H)-Phenanthrenemethanol, 1,3,4,10a-tetrahydro-7-hydroxy-1,1-dimethyl-8-(1-methylethyl)-, (4aR,10aS)-; 4aR,10aS Isomer of 1,3,4,10a-Tetrahydro-7-hydroxy-1,1-dimethyl-8-isopropyl-4aH-phenanthren-2-ol.
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems. Each batch undergoes comprehensive analytical characterization, including chiral purity verification by HPLC, to ensure identity, strength, and chemical purity. Certificates of Analysis (COA) detailing all relevant specifications are provided and available upon request, supporting compliance in regulated research environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The container should be kept in a well-ventilated area and protected from moisture. For long-term storage, consider an inert atmosphere to preserve stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% de
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.