Description

n-(3-Cyano-4,5,6,7-Tetrahydrobenzo[B]Thiophen-2-Yl)-[1,1-Biphenyl]-4-Carboxamide CAS NO 296266-10-9 is a high-purity, advanced pharmaceutical intermediate characterized by its complex heterocyclic structure. This compound is of significant value in medicinal chemistry for the research and development of novel therapeutic agents. It is primarily sought by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the synthesis of active pharmaceutical ingredients (APIs) and other bioactive molecules.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly in therapeutic areas targeting the central nervous system or metabolic disorders.
• Medicinal Chemistry Research: Used as a core scaffold or precursor for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Fine Chemical Synthesis: Serves as a specialized reagent for constructing complex molecular architectures containing tetrahydrobenzo[b]thiophene and biphenyl motifs.
• Biochemical Research: Potential use as a tool compound or inhibitor in biochemical assays to study specific enzyme or receptor interactions.
• Contract Manufacturing (CMO/CDMO): Supplied to contract manufacturing organizations for the production of clinical trial materials or niche APIs.

Basic Information

Product Name	n-(3-Cyano-4,5,6,7-Tetrahydrobenzo[B]Thiophen-2-Yl)-[1,1-Biphenyl]-4-Carboxamide
CAS No.	296266-10-9
Molecular Formula	C24H20N2OS
Molecular Weight	384.50 g/mol
Synonyms	4'-Biphenylcarboxylic acid [2-(3-cyano-4,5,6,7-tetrahydro-1-benzothien-2-yl)]amide; 2-[(4-Biphenylylcarbonyl)amino]-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carbonitrile; [1,1'-Biphenyl]-4-carboxamide, N-(3-cyano-4,5,6,7-tetrahydro-2-benzothienyl)-; Biphenyl-4-carboxylic acid (3-cyano-4,5,6,7-tetrahydro-benzo[b]thiophen-2-yl)-amide; CAS 296266-10-9
EINECS	Contact for details

Quality Control

Our n-(3-Cyano-4,5,6,7-Tetrahydrobenzo[B]Thiophen-2-Yl)-[1,1-Biphenyl]-4-Carboxamide is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements of pharmaceutical R&D. Certificates of Analysis (COA) detailing all specifications and test results are provided and can be tailored to meet specific client or regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This material is moisture-sensitive (hygroscopic) and should be handled under dry conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Any individual impurity ≤ 0.5%
Total Impurities	≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.