Description

4-Bromo-1-(Dibromomethyl)-2-Fluorobenzene is a halogenated aromatic building block of significant interest in advanced organic synthesis. Its unique structure, featuring bromine and fluorine substituents, makes it a versatile intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of fluorinated and brominated drug candidates, particularly in kinase inhibitors and CNS-active compounds.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the halogen atoms contribute to biological activity and metabolic stability.
• Material Science Precursor: Serves as a monomer or cross-linking agent in the synthesis of specialty polymers, liquid crystals, and organic electronic materials.
• Chemical Research: Employed in academic and industrial R&D for Suzuki, Stille, and other cross-coupling reactions to introduce functionalized aryl groups.
• Fluorine Chemistry: Acts as a valuable substrate for further functionalization, exploring the ortho-effect of fluorine in aromatic substitution reactions.

Basic Information

Product Name	4-Bromo-1-(Dibromomethyl)-2-Fluorobenzene
CAS No.	295803-26-8
Molecular Formula	C7H4Br3F
Molecular Weight	330.82 g/mol
Synonyms	2-Fluoro-4-bromo-α,α-dibromotoluene; 1-(Dibromomethyl)-4-bromo-2-fluorobenzene; 4-Bromo-α,α-dibromo-2-fluorotoluene; 2-Fluoro-4-bromobenzal bromide; (4-Bromo-2-fluorophenyl)dibromomethane; Benzene, 4-bromo-1-(dibromomethyl)-2-fluoro-; α,α-Dibromo-4-bromo-2-fluorotoluene
EINECS	Contact for details

Quality Control

Our 4-Bromo-1-(Dibromomethyl)-2-Fluorobenzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.