Description

1-[2-(1 H-Indol-3-Yl)-Ethyl]-5-Oxo-Pyrrolidine-3-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate characterized by its unique molecular architecture combining indole and pyrrolidone moieties. This compound is critical for research and development in medicinal chemistry, offering a versatile scaffold for the synthesis of novel bioactive molecules. It is primarily sought by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in developing new therapeutic agents, particularly for neurological and oncological targets.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Biochemical Reagent: Employed in enzymatic and receptor-binding assays as a potential inhibitor or modulator due to its structural features.
• Reference Standard: Provides a high-purity standard for analytical method development, validation, and quality control in API manufacturing.
• Precursor for Specialty Chemicals: Utilized in the synthesis of more complex, functionalized molecules for various life science applications.

Basic Information

Product Name	1-[2-(1 H-Indol-3-Yl)-Ethyl]-5-Oxo-Pyrrolidine-3-Carboxylic Acid
CAS No.	295344-74-0
Molecular Formula	C₁₅H₁₆N₂O₃
Molecular Weight	272.30 g/mol
Synonyms	5-Oxo-1-[2-(1H-indol-3-yl)ethyl]pyrrolidine-3-carboxylic acid; 1-[2-(1H-Indol-3-yl)ethyl]-5-oxopyrrolidine-3-carboxylic acid; 3-Carboxy-1-(2-indol-3-ylethyl)-2-pyrrolidinone; 295344-74-0; Pyrrolidine-3-carboxylic acid, 1-[2-(1H-indol-3-yl)ethyl]-5-oxo-; 1-(2-(1H-Indol-3-yl)ethyl)-5-oxopyrrolidine-3-carboxylic acid
EINECS	Contact for details

Quality Control

Our production of 1-[2-(1 H-Indol-3-Yl)-Ethyl]-5-Oxo-Pyrrolidine-3-Carboxylic Acid adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring full traceability and compliance with your research or cGMP-grade requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.