Description

Morpholine, 4-[(5-Bromo-2-Pyridinyl)Methyl]- (CAS NO 294851-95-9) is a specialized brominated pyridine derivative of morpholine, serving as a high-value pharmaceutical intermediate and organic synthesis building block. Its molecular structure, featuring both a morpholine ring and a halogenated pyridine moiety, makes it a critical precursor for the development of active pharmaceutical ingredients (APIs) and advanced agrochemicals. This compound is primarily sought by R&D chemists and process development scientists in the pharmaceutical and fine chemical industries for constructing complex molecules with targeted biological activity.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly in kinase inhibitor and central nervous system (CNS) therapeutic research.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, where the bromopyridine unit acts as a crucial pharmacophore.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in transition metal catalysis and organometallic chemistry.
• Material Science Research: Employed in the synthesis of functionalized polymers and organic electronic materials due to its heterocyclic structure.
• Chemical Biology Probes: Utilized to create tagged molecules for studying biological pathways and protein interactions.
• Custom Synthesis and Contract Manufacturing: A vital starting material for custom synthesis projects requiring a specific, functionalized morpholine scaffold.

Basic Information

Product Name	Morpholine, 4-[(5-Bromo-2-Pyridinyl)Methyl]-
CAS No.	294851-95-9
Molecular Formula	C10H13BrN2O
Molecular Weight	257.13 g/mol
Synonyms	4-[(5-Bromo-2-pyridinyl)methyl]morpholine; 5-Bromo-2-(morpholin-4-ylmethyl)pyridine; N-[(5-Bromopyridin-2-yl)methyl]morpholine; 2-[(Morpholin-4-yl)methyl]-5-bromopyridine; 5-Bromo-2-morpholinomethylpyridine; 4-(5-Bromo-2-pyridylmethyl)morpholine; (5-Bromo-2-pyridylmethyl)morpholine
EINECS	Contact for details

Quality Control

Our production of Morpholine, 4-[(5-Bromo-2-Pyridinyl)Methyl]- adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity for sensitive synthetic applications. Each lot is characterized by advanced analytical techniques including HPLC, GC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment. We support cGMP compliance for pharmaceutical intermediate applications, and our quality system is designed to meet the rigorous standards of global regulatory frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed to prevent moisture absorption and contamination. Store away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%, Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.