Description

3,4,5-Trihydroxybenzoic-2,6-D2 Acid is a deuterated derivative of gallic acid, a naturally occurring polyphenol. This isotopically labeled compound is essential for advanced analytical and research applications where precise molecular tracking and quantification are required. It is primarily utilized by researchers and manufacturers in the pharmaceutical, agrochemical, and analytical chemistry sectors for use as an internal standard in mass spectrometry, metabolic pathway studies, and the synthesis of labeled complex molecules.

Application

• Internal Standard for Mass Spectrometry (MS): Provides high-accuracy quantification in LC-MS and GC-MS analysis of gallic acid and related polyphenols in complex matrices.
• Metabolic Tracing Studies: Used in pharmacokinetic and drug metabolism research to track the absorption, distribution, metabolism, and excretion (ADME) of gallic acid derivatives.
• Synthesis of Deuterated Compounds: Serves as a key building block for the preparation of more complex deuterium-labeled molecules for research and development.
• NMR Spectroscopy Solvent: Acts as a useful probe in nuclear magnetic resonance (NMR) spectroscopy due to the distinct signal of deuterium atoms.
• Pharmaceutical Impurity Profiling: Aids in the identification and quantification of process-related impurities and degradation products in drug formulations containing gallate esters.
• Food & Nutraceutical Analysis: Enables precise measurement of gallic acid content and its metabolites in food, beverages, and dietary supplements.

Basic Information

Product Name	3,4,5-Trihydroxybenzoic-2,6-D2 Acid
CAS No.	294660-92-7
Molecular Formula	C7H4D2O5
Molecular Weight	172.13 g/mol
Synonyms	Gallic Acid-2,6-D2; 3,4,5-Trihydroxybenzoic Acid-d2; Deuterated Gallic Acid; Gallic Acid (2,6-dideutero); Benzoic Acid, 3,4,5-trihydroxy-2,6-dideutero; 2,6-Dideuterogallic Acid
EINECS	Contact for details

Quality Control

Our 3,4,5-Trihydroxybenzoic-2,6-D2 Acid is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including NMR and Mass Spectrometry, to confirm isotopic purity, chemical identity, and overall purity. Certificates of Analysis (COA) detailing the isotopic enrichment (D atom% at specified positions), chemical purity, and impurity profile are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is easily oxidized; for long-term storage, consider keeping under an inert atmosphere such as argon or nitrogen. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (NMR/MS)	≥ 98.0 atom % D (at specified positions)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.