Description

2-Mercapto-5-Phenyl-3H-Thieno[2,3-D]Pyrimidin-4-One is a specialized heterocyclic compound that serves as a critical building block in advanced organic synthesis. Its unique fused-ring structure containing sulfur and nitrogen atoms makes it a valuable intermediate for developing novel active pharmaceutical ingredients (APIs) and functional materials. This high-purity intermediate is essential for research and production in pharmaceutical chemistry, agrochemical development, and materials science, where precise molecular architecture is paramount.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of novel drug candidates, particularly in kinase inhibitor and antiviral therapeutic areas.
• Agrochemical Research: Used in the synthesis of new-generation herbicides, fungicides, and plant growth regulators.
• Organic Electronic Materials: Serves as a precursor for constructing complex π-conjugated systems used in organic light-emitting diodes (OLEDs) and semiconductors.
• Chemical Biology Probes: Utilized in the design of molecular probes and inhibitors for studying enzyme mechanisms and cellular pathways.
• Coordination Chemistry: Acts as a ligand for metal complexes in catalysis and materials science due to its mercapto and heterocyclic nitrogen donor sites.
• Academic & Industrial R&D: A fundamental reagent for methodological studies in heterocyclic and medicinal chemistry.

Basic Information

Product Name	2-Mercapto-5-Phenyl-3H-Thieno[2,3-D]Pyrimidin-4-One
CAS No.	294653-45-5
Molecular Formula	C₁₂H₈N₂OS₂
Molecular Weight	260.33 g/mol
Synonyms	5-Phenyl-4-oxo-3,4-dihydrothieno[2,3-d]pyrimidine-2-thiol; 2-Thioxo-5-phenyl-1,2-dihydro-3H-thieno[2,3-d]pyrimidin-4-one; 2-Mercapto-5-phenyl-3H-thieno[2,3-d]pyrimidin-4(5H)-one; Thieno[2,3-d]pyrimidine-2-thiol, 5-phenyl-4-oxo-3,4-dihydro-; 294653-45-5; 5-Phenyl-2-sulfanylidene-1,3-dihydrothieno[2,3-d]pyrimidin-4-one
EINECS	Contact for details

Quality Control

Our 2-Mercapto-5-Phenyl-3H-Thieno[2,3-D]Pyrimidin-4-One is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific customer or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to store the product under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.