Description

1H-Indole-2-Carboxylicacid,2,3-Dihydro-,Methylester,(2R)-(9Ci) is a high-purity chiral indole derivative, a critical building block in advanced organic synthesis. Its defined stereochemistry and functionalized indole scaffold make it an essential intermediate for creating complex molecules with high biological relevance. This compound is primarily sought by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new therapeutic agents, particularly in central nervous system (CNS) and oncology drug candidates.
• Agrochemical Synthesis: Used in the creation of advanced, biologically active compounds for crop protection and pest management solutions.
• Asymmetric Catalysis Research: Serves as a valuable substrate or ligand precursor in the study and development of new stereoselective synthetic methodologies.
• Fine Chemical Production: Employed in the multi-step synthesis of complex, high-value specialty chemicals and flavors & fragrances.
• Academic & R&D Laboratories: A fundamental reagent for synthetic organic chemistry research, enabling the exploration of new indole-based molecular architectures.

Basic Information

Product Name	1H-Indole-2-Carboxylicacid,2,3-Dihydro-,Methylester,(2R)-(9Ci)
CAS No.	293737-30-1
Molecular Formula	C11H11NO2
Molecular Weight	189.21 g/mol
Synonyms	(2R)-2,3-Dihydro-1H-indole-2-carboxylic acid methyl ester; Methyl (2R)-2,3-dihydro-1H-indole-2-carboxylate; (R)-Methyl indoline-2-carboxylate; (R)-Indoline-2-carboxylic acid methyl ester; (R)-2-Carbomethoxyindoline; (R)-Methyl 2,3-dihydro-1H-indole-2-carboxylate; (R)-1,2,3,4-Tetrahydro-2-quinolinecarboxylic acid methyl ester (related structure); (9CI) designation for CAS indexing.
EINECS	Contact for details

Quality Control

Our production of this chiral intermediate adheres to strict quality management protocols, ensuring batch-to-batch consistency and high chemical purity. Each lot is characterized using advanced analytical techniques including chiral HPLC, NMR, and MS to confirm identity, enantiomeric excess, and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We support cGMP-grade production for advanced pharmaceutical applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound may be hygroscopic; keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.