Description

3-Isoquinolinecarboxylicacid,7-Amino-1,2,3,4-Tetrahydro-,Methylester,(3S)-(9Ci) CAS NO 293736-97-7 is a high-purity, stereochemically defined isoquinoline derivative, serving as a critical chiral building block in advanced organic synthesis. Its value lies in providing a structurally complex, enantiomerically pure scaffold essential for constructing pharmacologically active molecules. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the development of new therapeutic agents, particularly within medicinal chemistry and process R&D.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of novel drug candidates targeting central nervous system (CNS) disorders, cardiovascular diseases, and other therapeutic areas.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs due to its rigid, fused-ring structure and functional handles for derivatization.
• Asymmetric Synthesis: Employed as a starting material or intermediate in catalytic asymmetric reactions to construct complex, enantiomerically enriched molecules.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme function and biological pathways.
• Process Chemistry Development: Serves as a reference standard or an intermediate in scaling up synthetic routes from laboratory to pilot plant scale.
• Academic Research: Used in university and institutional labs for methodological development in organic synthesis and heterocyclic chemistry.

Basic Information

Product Name	3-Isoquinolinecarboxylicacid,7-Amino-1,2,3,4-Tetrahydro-,Methylester,(3S)-(9Ci)
CAS No.	293736-97-7
Molecular Formula	C11H14N2O2
Molecular Weight	206.24 g/mol
Synonyms	(3S)-7-Amino-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid methyl ester; Methyl (3S)-7-amino-1,2,3,4-tetrahydro-3-isoquinolinecarboxylate; (S)-Methyl 7-amino-3,4-dihydro-1H-isoquinoline-3-carboxylate; 7-Amino-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid methyl ester, (3S)-; (3S)-7-Amino-3,4-dihydro-1H-isoquinoline-3-carboxylic acid methyl ester; ATIQ-CM ester (S-enantiomer); A chiral tetrahydroisoquinoline derivative
EINECS	Contact for details

Quality Control

Our production of 3-Isoquinolinecarboxylicacid,7-Amino-1,2,3,4-Tetrahydro-,Methylester,(3S)-(9Ci) adheres to stringent quality management protocols to ensure batch-to-batch consistency and high chemical purity. Each lot is fully characterized and tested using advanced analytical techniques including HPLC, GC, NMR, and chiral analysis. Certificates of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profiles are provided with every shipment to support your regulatory and research documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if specified. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.