Description

3-[[[1-Methyl-3-(Trifluoromethyl)-1H-Pyrazol-4-Yl]Carbonyl]Amino]-2-Thiophenecarboxylic Acid Methyl Ester is a high-value, multi-functional heterocyclic building block designed for advanced chemical synthesis. This compound matters for its unique molecular architecture, combining a trifluoromethylpyrazole moiety with a thiophene carboxylic acid ester, which is critical for imparting specific biological activity and physicochemical properties to target molecules. It is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for creating novel active ingredients, particularly in the development of crop protection agents and potential pharmaceutical intermediates.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the research and development of new drug candidates, particularly those targeting enzyme inhibition.
• Agrochemical Synthesis: A crucial precursor for the development of next-generation herbicides, fungicides, and insecticides, leveraging the bioactivity of the pyrazole and thiophene rings.
• Material Science Research: Used in the synthesis of specialized polymers and organic electronic materials due to its conjugated system and fluorine content.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying biological pathways and target engagement.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds for client projects.

Basic Information

Product Name	3-[[[1-Methyl-3-(Trifluoromethyl)-1H-Pyrazol-4-Yl]Carbonyl]Amino]-2-Thiophenecarboxylic Acid Methyl Ester
CAS No.	293326-85-9
Molecular Formula	C12H10F3N3O3S
Molecular Weight	333.28 g/mol
Synonyms	Methyl 3-({[1-methyl-3-(trifluoromethyl)-1H-pyrazol-4-yl]carbonyl}amino)thiophene-2-carboxylate; 3-({[1-Methyl-3-(trifluoromethyl)-1H-pyrazol-4-yl]carbonyl}amino)-2-thiophenecarboxylic acid methyl ester; 2-Thiophenecarboxylic acid, 3-[[[1-methyl-3-(trifluoromethyl)-1H-pyrazol-4-yl]carbonyl]amino]-, methyl ester; Methyl 3-[[[1-methyl-3-(trifluoromethyl)pyrazol-4-yl]carbonyl]amino]thiophene-2-carboxylate; CAS 293326-85-9
EINECS	Contact for details

Quality Control

Our 3-[[[1-Methyl-3-(Trifluoromethyl)-1H-Pyrazol-4-Yl]Carbonyl]Amino]-2-Thiophenecarboxylic Acid Methyl Ester is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (NMR, IR, MS), to ensure it meets the high standards required for research and scale-up activities. A detailed Certificate of Analysis (COA) is provided with each shipment, guaranteeing traceability and consistent quality for your critical synthesis work.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. For long-term storage, a temperature of 2-8°C is recommended to maintain stability. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.