Description

1,2-Benzene-D4-Diamine is a deuterium-labeled analog of ortho-phenylenediamine, a critical building block in advanced chemical synthesis. This isotopically labeled compound is essential for applications requiring precise molecular tracking and analysis, such as in mass spectrometry and NMR spectroscopy. It is primarily utilized by researchers and manufacturers in the pharmaceutical, agrochemical, and analytical chemistry sectors for developing and testing new compounds, including deuterated active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Research & Development: As a deuterated precursor for synthesizing isotopically labeled drug candidates and metabolites for pharmacokinetic and metabolic stability studies.
• Analytical Chemistry Standards: Serving as an internal standard in quantitative mass spectrometry (LC-MS, GC-MS) for accurate measurement of o-phenylenediamine and related compounds.
• Agrochemical Development: Used in the synthesis of deuterated pesticides and herbicides to study environmental fate, degradation pathways, and residue analysis.
• Material Science: A key monomer for creating specialized polymers and dyes with modified physical or spectroscopic properties.
• NMR Spectroscopy: Employed as a probe or tracer in mechanistic studies and structural analysis due to its distinct deuterium NMR signal.
• Chemical Biology: Useful in proteomics and biomarker discovery for labeling and tracking biological molecules.

Basic Information

Product Name	1,2-Benzene-D4-Diamine
CAS No.	291765-93-0
Molecular Formula	C6D4(NH2)2
Molecular Weight	116.17 g/mol
Synonyms	1,2-Diaminobenzene-d4; o-Phenylenediamine-d4; 1,2-Benzenediamine-d4; o-Diaminobenzene-d4; 1,2-Diamino-3,4,5,6-tetradeuteriobenzene; Benzene-3,4,5,6-d4-1,2-diamine; OPDA-d4; Isotopic Labeled o-Phenylenediamine
EINECS	Contact for details

Quality Control

Our 1,2-Benzene-D4-Diamine is manufactured under strict quality protocols to ensure high isotopic purity and chemical integrity. Each batch is characterized by advanced analytical techniques including NMR and Mass Spectrometry to confirm deuterium incorporation and chemical purity. A comprehensive Certificate of Analysis (COA) detailing isotopic enrichment (typically >98 atom % D), chemical purity, and other critical parameters is provided with every shipment to support your research and compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) and easily oxidized nature, it is recommended to handle under an inert atmosphere (e.g., nitrogen or argon) for long-term storage and to minimize exposure to air during use.

Specification

Item	Specification
Appearance	White to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (Atom % D)	≥ 98%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.