Description

3-Thiophenecarboxylicacid,2,5-Dibromo-,Ethylester(9Ci) CAS NO 289470-44-6 is a high-purity, functionalized thiophene derivative, specifically the ethyl ester of 2,5-dibromothiophene-3-carboxylic acid. This compound serves as a critical advanced pharmaceutical intermediate (API intermediate) and a versatile organic synthesis building block for constructing complex heterocyclic systems. It is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science sectors who require precise bromination patterns on the thiophene scaffold for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Building block for developing new generation pesticides and herbicides with specific activity profiles.
• Organic Electronic Materials: Used in research and development of conjugated polymers and small molecules for organic light-emitting diodes (OLEDs) and organic photovoltaics (OPVs).
• Ligand and Catalyst Development: Serves as a functionalized backbone for creating specialized ligands used in transition metal catalysis.
• Chemical Research & Development: A versatile reagent for academic and industrial R&D focused on heterocyclic chemistry and cross-coupling reactions (e.g., Suzuki, Stille).
• Specialty Fine Chemicals: Intermediate for the production of dyes, pigments, and other performance chemicals where the thiophene moiety imparts specific properties.

Basic Information

Product Name	3-Thiophenecarboxylicacid,2,5-Dibromo-,Ethylester(9Ci)
CAS No.	289470-44-6
Molecular Formula	C7H6Br2O2S
Molecular Weight	313.99 g/mol
Synonyms	Ethyl 2,5-Dibromothiophene-3-carboxylate; 2,5-Dibromothiophene-3-carboxylic Acid Ethyl Ester; 3-Thiophenecarboxylic acid, 2,5-dibromo-, ethyl ester; Ethyl 2,5-dibromo-3-thiophenecarboxylate; 2,5-Dibromo-3-thiophenecarboxylic acid ethyl ester; 289470-44-6; AI3-52310
EINECS	Contact for details

Quality Control

Our production of Ethyl 2,5-Dibromothiophene-3-carboxylate adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity for sensitive applications. Each lot undergoes comprehensive analysis including HPLC for purity, GC for residual solvents, and NMR/IR for structural confirmation. We provide detailed Certificates of Analysis (COA) with every shipment, documenting all critical quality attributes. Our quality management system is designed to support cGMP requirements for advanced intermediate manufacturing.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to minimize exposure to moisture. Store away from incompatible materials such as strong acids and strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.