Description

D-[2-2H]Xylose is a stable isotope-labeled analog of the pentose sugar D-xylose, specifically deuterated at the 2-position. This compound is an essential tool for advanced metabolic and biochemical research, providing a non-radioactive tracer for precise pathway analysis. It is primarily used by researchers and manufacturers in the pharmaceutical, biotechnology, and analytical chemistry sectors for applications requiring high isotopic purity and chemical stability.

Application

• Metabolic Pathway Tracing: Used as a stable isotope tracer in in vitro and in vivo studies to elucidate xylose metabolism and pentose phosphate pathway dynamics.
• Pharmaceutical Research: Serves as a key intermediate or analytical standard in the development and testing of drugs targeting carbohydrate metabolism.
• Quantitative Mass Spectrometry: Acts as an internal standard for the accurate quantification of D-xylose and related metabolites in complex biological matrices via LC-MS or GC-MS.
• Biochemical Assay Development: Employed in enzyme activity assays (e.g., for xylose isomerase or xylulokinase) to study kinetics and inhibition without radioactive hazards.
• Nutritional Science Research: Used in studies investigating dietary fiber fermentation, gut microbiome metabolism, and short-chain fatty acid production.
• Isotope Dilution Analysis: Provides a high-purity reference standard for precise calibration and method validation in analytical laboratories.

Basic Information

Product Name	D-[2-2H]Xylose
CAS No.	288846-91-3
Molecular Formula	C5H9D1O5
Molecular Weight	151.13 g/mol (for monodeuterated form)
Synonyms	D-Xylose-2-d; Deuterated D-Xylose; (2R,3S,4R)-2,3,4,5-Tetrahydroxypentanal-2-d; 2-Deuterio-D-xylose; D-Xylopyranose-2-d; Stable Isotope Labeled D-Xylose; D-Xylose (2-2H); Wood Sugar-2-d
EINECS	Contact for details

Quality Control

Every batch of D-[2-2H]Xylose is manufactured and tested under strict quality management systems. We ensure high isotopic purity and chemical purity through advanced analytical techniques including NMR, HPLC, and Mass Spectrometry. A comprehensive Certificate of Analysis (COA) detailing isotopic enrichment, chemical purity, and specific tests is provided with each shipment to guarantee consistency and reliability for your critical research applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive). For long-term storage, consider desiccation or storage under an inert atmosphere to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Enrichment	≥ 98 atom % 2H
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Specific Optical Rotation	+18.5° to +19.5° (c=10 in H2O)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.