Description

2H-1,3-Oxazine-2,6(3H)-Dione,Dihydro-4-(1-Methylethyl)-,(4R)-(9Ci) is a high-purity, stereochemically defined chiral intermediate of significant importance in advanced organic synthesis. Its value lies in its role as a key building block for constructing complex molecules with specific three-dimensional architectures, which is critical for developing pharmaceuticals and agrochemicals with targeted biological activity. This compound, identified by CAS No. 288623-03-0, is primarily sought after by R&D chemists and process development scientists in the pharmaceutical and fine chemical industries.

Application

• Pharmaceutical Intermediate: Serves as a crucial chiral synthon in the synthesis of active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) agents and other therapeutic compounds requiring specific stereochemistry.
• Agrochemical Synthesis: Used in the research and development of novel, enantiomerically pure pesticides and herbicides where biological activity is stereospecific.
• Asymmetric Catalysis Research: Acts as a precursor or ligand in the development of new chiral catalysts for stereoselective reactions.
• Fine Chemical Production: Employed in the multi-step synthesis of complex, high-value specialty chemicals and flavors/fragrances.
• Academic & Industrial R&D: A valuable tool for methodological studies in organic chemistry, enabling the exploration of new synthetic routes to chiral lactam and heterocyclic frameworks.

Basic Information

Product Name	2H-1,3-Oxazine-2,6(3H)-Dione,Dihydro-4-(1-Methylethyl)-,(4R)-(9Ci)
CAS No.	288623-03-0
Molecular Formula	C7H11NO3
Molecular Weight	157.17 g/mol
Synonyms	(4R)-4-Isopropyl-dihydro-2H-1,3-oxazine-2,6(3H)-dione; (R)-4-Isopropyl-1,3-oxazane-2,6-dione; 4-Isopropyl-dihydro-2H-1,3-oxazine-2,6(3H)-dione, (4R)-; (R)-4-(1-Methylethyl)-2H-1,3-oxazine-2,6(3H)-dione, dihydro-; (4R)-4-(Propan-2-yl)-3,4-dihydro-2H-1,3-oxazine-2,6-dione; Chiral 4-isopropyl-dihydro-oxazinedione; (R)-enantiomer of 4-isopropyl-1,3-oxazane-2,6-dione
EINECS	Contact for details

Quality Control

Our production of this chiral intermediate adheres to strict quality management protocols to ensure batch-to-batch consistency and high enantiomeric purity. Each lot is characterized using advanced analytical techniques including Chiral HPLC and NMR spectroscopy to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing chiral purity, chemical purity, and residual solvent levels is provided with every shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, open flames, and incompatible materials. For long-term storage, consider inert gas purging to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.