Description

8-Indolizinemethanamine,5,6,7,8-Tetrahydro-,(8R)-(9Ci) is a high-purity, chiral indolizine derivative of significant interest in advanced organic synthesis. This compound serves as a sophisticated building block for the development of novel pharmaceutical intermediates and bioactive molecules. It is primarily utilized by research institutions and pharmaceutical companies engaged in medicinal chemistry, particularly for the synthesis of complex heterocyclic compounds targeting neurological and metabolic pathways. Its defined stereochemistry at the 8-position provides a critical handle for creating enantiomerically pure drug candidates.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs), especially for central nervous system (CNS) targets.
• Medicinal Chemistry Research: Used as a core scaffold for constructing libraries of novel heterocyclic compounds in drug discovery programs.
• Asymmetric Synthesis: Employed as a building block in catalytic asymmetric reactions to introduce complex molecular architecture.
• Biochemical Research: Potential use in the study of enzyme inhibitors or receptor ligands due to its specific structural features.
• Fine Chemical Synthesis: Serves as a precursor for the manufacture of specialty chemicals requiring the indolizine framework.

Basic Information

Item	Detail
Product Name	8-Indolizinemethanamine,5,6,7,8-Tetrahydro-,(8R)-(9Ci)
CAS No.	288588-14-7
Molecular Formula	C11H16N2
Molecular Weight	176.26 g/mol
Synonyms	(8R)-5,6,7,8-Tetrahydro-8-indolizinemethanamine; (R)-5,6,7,8-Tetrahydro-8-indolizinemethylamine; (8R)-5,6,7,8-Tetrahydroindolizine-8-methanamine; 8-Indolizinemethanamine, 5,6,7,8-tetrahydro-, (8R)-; (R)-8-(Aminomethyl)-5,6,7,8-tetrahydroindolizine; Tetrahydroindolizine derivative 288588-14-7
EINECS	Contact for details

Quality Control

Every batch of our 8-Indolizinemethanamine,5,6,7,8-Tetrahydro-,(8R)-(9Ci) is produced and tested under strict quality management protocols to ensure high chemical purity and enantiomeric excess. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, chiral purity, and impurity profiles. Our quality systems are designed to support cGMP and ISO standards for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This material is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere if possible to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.