Description

3(2H)-Indolizinone,1,5,8,8A-Tetrahydro-,(8As)-(9Ci) is a high-purity, advanced pharmaceutical intermediate and versatile heterocyclic building block. Its unique fused bicyclic structure makes it a critical precursor for synthesizing complex molecules in medicinal chemistry and fine chemical research. This compound is essential for R&D scientists and process chemists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop novel active ingredients.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new therapeutic agents, particularly in central nervous system (CNS) and anti-infective drug candidates.
• Medicinal Chemistry Research: Serves as a privileged scaffold for constructing compound libraries and exploring structure-activity relationships (SAR) in drug discovery programs.
• Agrochemical Synthesis: Used as a building block in the development of novel pesticides and herbicides with specific biological activity.
• Fine Chemical Production: Employed in the multi-step synthesis of complex, high-value specialty chemicals and functional materials.
• Academic & Institutional R&D: A valuable reagent for universities and research institutes conducting studies in organic synthesis and heterocyclic chemistry.
• Process Chemistry & Scale-Up: Suitable for optimization and pilot-scale production runs for new chemical entities (NCEs).

Basic Information

Product Name	3(2H)-Indolizinone,1,5,8,8A-Tetrahydro-,(8As)-(9Ci)
CAS No.	287974-12-3
Molecular Formula	C8H9NO
Molecular Weight	135.16 g/mol
Synonyms	(8aS)-1,5,8,8a-Tetrahydro-3(2H)-indolizinone; (8aS)-Octahydro-3(2H)-indolizinone; 1,5,8,8a-Tetrahydro-3(2H)-indolizinone, (8aS)-; 287974-12-3; 3(2H)-Indolizinone, 1,5,8,8a-tetrahydro-, (8aS)-; (8aS)-1,2,5,6,7,8,8a,9-Octahydro-3H-indolizin-3-one
EINECS	Contact for details

Quality Control

Our 3(2H)-Indolizinone,1,5,8,8A-Tetrahydro-,(8As)-(9Ci) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and chiral purity assessment, to ensure it meets the high standards required for research and development applications. A Certificate of Analysis (COA) detailing identity, purity, and impurity profile is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.