Description

1H-Indole,2,3-Dihydro-1,3-Dimethyl-,(3R)-(9Ci) is a chiral, substituted indoline derivative of significant interest in advanced organic synthesis. This compound matters as a versatile and high-purity chiral building block, enabling the construction of complex molecules with precise stereochemistry. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of active pharmaceutical ingredients (APIs) and other biologically active compounds.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel therapeutic agents, particularly for central nervous system (CNS) targets.
• Agrochemical Synthesis: Used in the creation of advanced, stereospecific pesticides and herbicides where the specific (3R) configuration is critical for bioactivity.
• Asymmetric Catalysis Research: Serves as a ligand precursor or a test substrate in the development of new chiral catalysts and methodologies.
• Fine Chemical Production: Employed in the multistep synthesis of complex natural products, flavors, and fragrances requiring indoline scaffolds.
• Academic & Institutional R&D: Utilized in university and government laboratories for fundamental studies in heterocyclic and medicinal chemistry.

Basic Information

Product Name	1H-Indole,2,3-Dihydro-1,3-Dimethyl-,(3R)-(9Ci)
CAS No.	287933-37-3
Molecular Formula	C11H15N
Molecular Weight	161.24 g/mol
Synonyms	(3R)-1,3-Dimethyl-2,3-dihydro-1H-indole; (R)-1,3-Dimethylindoline; (R)-N,1-Dimethyl-2,3-dihydro-1H-indol-3-amine; 1H-Indole, 2,3-dihydro-1,3-dimethyl-, (3R)-; (R)-1,3-Dimethyl-2,3-dihydroindole; (R)-1,3-Dimethylindoline; 287933-37-3; (R)-N-Methyl-1-methylindolin-3-amine
EINECS	Contact for details

Quality Control

Our 1H-Indole,2,3-Dihydro-1,3-Dimethyl-,(3R)-(9Ci) is produced under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high chemical and chiral purity, meeting the exacting standards required for research and process chemistry. A comprehensive Certificate of Analysis (COA) detailing identity, purity (by HPLC/GC), chiral purity, and impurity profile is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep away from heat sources and incompatible materials. The product is light-sensitive and should be stored away from light.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC/GC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.