Description

Toluene-13C6 is a stable isotope-labeled analog of toluene, where all six carbon atoms are the carbon-13 isotope. This compound is essential for applications requiring high-precision internal standards and tracer studies, providing unmatched accuracy in quantitative analysis. It is a critical reagent for researchers and quality control laboratories in the pharmaceutical, environmental, and metabolomics fields, where precise measurement and tracking of toluene or related compounds are necessary.

Application

• Quantitative Analytical Internal Standard: Used as a certified reference material in Gas Chromatography-Mass Spectrometry (GC-MS) and Liquid Chromatography-Mass Spectrometry (LC-MS) for the accurate quantification of toluene in complex matrices.
• Metabolic Pathway Tracing: Serves as a tracer in biomedical and environmental research to study the biodegradation, metabolic fate, and transformation pathways of toluene and related aromatic compounds.
• NMR Spectroscopy Solvent & Standard: Employed as a solvent or chemical shift reference standard in Nuclear Magnetic Resonance (NMR) spectroscopy due to its defined isotopic purity.
• Pharmaceutical Impurity Profiling: Critical for method development and validation in pharmaceutical analysis to detect and quantify toluene residues as a genotoxic impurity (GTI) in active pharmaceutical ingredients (APIs) and drug products.
• Environmental Monitoring: Used in the calibration of instruments and validation of methods for monitoring toluene contamination in air, water, and soil samples to ensure regulatory compliance.
• Isotope Dilution Mass Spectrometry (IDMS): Acts as the spike material in IDMS, the gold-standard technique for achieving highest accuracy and traceability in clinical and forensic toxicology.

Basic Information

Product Name	Toluene-13C6
CAS No.	287399-35-3
Molecular Formula	13C6H5CH3
Molecular Weight	100.11 g/mol
Synonyms	Methyl-13C6-benzene; Toluene-13C6 (Ring-13C6); [13C6]-Toluene; Toluene (13C6); Benzene, methyl-13C6-; 13C Labeled Toluene; Isotopic Toluene; Toluene (ring-13C6); Toluene-13C (Ring Labeled)
EINECS	Contact for details

Quality Control

Every batch of Toluene-13C6 is manufactured and analyzed under strict quality management systems. We guarantee high chemical and isotopic purity, with comprehensive testing including assay, isotopic enrichment, and identification. Certificates of Analysis (COA) are provided, detailing batch-specific results for parameters such as purity by GC, isotopic abundance by NMR or MS, and solvent residues. Our quality commitment ensures reliability for your most demanding analytical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated area away from heat and ignition sources. Recommended storage temperature is 2-8°C to maintain stability and minimize volatility. Keep container tightly sealed when not in use to prevent evaporation and contamination.

Specification

Item	Specification
Appearance	Clear Colorless Liquid
Identification (IR)	Conforms to Structure
Assay (GC)	≥ 99.0% (Chemical Purity)
Isotopic Enrichment	≥ 99 atom % 13C
Water Content (KF)	≤ 0.1%
Residual Solvents (GC)	Meets ICH Guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.