Description

Diethyl-D10 Chlorothiophosphate is a deuterated isotopologue of diethyl chlorothiophosphate, where ten hydrogen atoms are replaced by deuterium. This high-purity labeled compound is critical for advanced research and development, particularly in mechanistic studies and analytical method development where isotopic tracing is required. It serves as a key intermediate and reference standard for scientists in pharmaceutical development, agrochemical research, and analytical chemistry.

Application

• Isotopic Labeling in Synthesis: Used as a deuterium-labeled building block for synthesizing isotopically labeled organophosphorus compounds for metabolic and environmental fate studies.
• Internal Standard for Mass Spectrometry: Serves as a high-purity internal standard in LC-MS and GC-MS analysis for the accurate quantification of its non-deuterated counterpart and related metabolites.
• Mechanistic Probe: Employed in reaction mechanism elucidation within medicinal chemistry and pesticide development, leveraging deuterium kinetic isotope effects (DKIE).
• Reference Material: Acts as a certified reference material (CRM) for calibrating analytical instruments and validating methods in quality control laboratories.
• Precursor for Labeled Agrochemicals: Key intermediate in the synthesis of deuterated analogs of insecticides and herbicides for advanced R&D.

Basic Information

Product Name	Diethyl-D10 Chlorothiophosphate
CAS No.	287397-89-1
Molecular Formula	C4D10ClO2PS
Molecular Weight	204.64 (for C4D10ClO2PS)
Synonyms	Deuterated Diethyl Chlorothiophosphate; Diethyl-d10 Thiophosphoryl Chloride; O,O-Diethyl-d10 Phosphorochloridothioate; Chlorothiophosphoric Acid O,O-Diethyl-d10 Ester; (CD3CD2O)2P(S)Cl; Diethyl-D10 Thiophosphorochloridate; Ethyl-d5 Chlorothiophosphate
EINECS	Contact for details

Quality Control

Every batch of Diethyl-D10 Chlorothiophosphate is manufactured and analyzed under strict quality management protocols to ensure exceptional isotopic and chemical purity. Our products undergo rigorous quality testing, including advanced spectroscopic and chromatographic methods, to ensure compliance with research and analytical standards. Comprehensive Certificates of Analysis (COA) detailing isotopic purity (D-enrichment), chemical assay, and impurity profiles are provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening. Keep away from strong acids and incompatible organic solvents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC / HPLC)	≥ 98.0%
Isotopic Purity (D-enrichment)	≥ 98 atom % D
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.