Description

Sodium 4-Methylvalerate-1-13C is a stable, isotopically labeled sodium salt of 4-methylvaleric acid, where the carbon-13 isotope is specifically incorporated at the carboxyl position. This precise labeling makes it an essential internal standard and tracer for advanced metabolic and pharmacokinetic studies using mass spectrometry and NMR spectroscopy. It is primarily required by pharmaceutical R&D laboratories, contract research organizations (CROs), and academic institutions engaged in drug development, biomarker discovery, and detailed metabolic pathway analysis.

Application

• Internal Standard for Quantitative Analysis: Used in LC-MS and GC-MS methods for the accurate quantification of endogenous metabolites or drug compounds in complex biological matrices.
• Metabolic Tracer Studies: Enables the tracking of specific metabolic fluxes and pathways in in vitro and in vivo systems to understand disease mechanisms or drug metabolism.
• Stable Isotope Labeling in Pharmaceutical Research: Critical for conducting Absorption, Distribution, Metabolism, and Excretion (ADME) studies during preclinical drug development.
• NMR Spectroscopy: Serves as a labeled reference compound for structural elucidation and dynamic studies in nuclear magnetic resonance experiments.
• Biomarker Research: Assists in the development and validation of assays for potential disease biomarkers related to branched-chain fatty acid metabolism.
• Quality Control Reference Material: Employed as a certified reference material to ensure the accuracy and precision of analytical methods in quality control laboratories.

Basic Information

Product Name	Sodium 4-Methylvalerate-1-13C
CAS No.	287111-41-5
Molecular Formula	C5H913COONa
Molecular Weight	Contact for details
Synonyms	Sodium 4-Methylpentanoate-1-13C; Sodium Isocaproate-1-13C; 4-Methylvaleric Acid-1-13C Sodium Salt; Isohexanoic Acid-1-13C Sodium Salt; (1-13C)-4-Methylpentanoic Acid Sodium Salt; Sodium (1-13C)-4-Methylvalerate; 13C Labeled Sodium 4-Methylvalerate
EINECS	Contact for details

Quality Control

Every batch of Sodium 4-Methylvalerate-1-13C CAS NO 287111-41-5 is manufactured under controlled conditions and undergoes rigorous analytical testing to ensure exceptional isotopic and chemical purity, critical for sensitive research applications. Our quality commitment includes traceability and compliance with relevant standards for research chemicals. A comprehensive Certificate of Analysis (COA) detailing isotopic enrichment, assay, purity, and identification is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Enrichment	≥ 99 atom % 13C
Chemical Purity (NMR)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.