Description

D-Glucose-1,6-13C2 is a stable isotope-labeled analog of glucose, specifically enriched with carbon-13 at the 1 and 6 positions. This high-purity compound is essential for advanced metabolic research, enabling precise tracking and quantification of glucose utilization pathways. It is a critical reagent for scientists and manufacturers in pharmaceutical development, clinical diagnostics, and nutritional research who require reliable, high-quality isotopic tracers.

Application

• Metabolic Flux Analysis (MFA): Used as a tracer to map and quantify intracellular metabolic pathways in cell cultures, tissues, and whole organisms.
• Drug Metabolism and Pharmacokinetics (DMPK): Serves as an internal standard in LC-MS/MS and GC-MS assays for the accurate quantification of glucose and its metabolites in biological samples.
• Clinical Research: Enables studies on glucose metabolism disorders, such as diabetes and cancer, by providing a precise tool to monitor glycolytic and pentose phosphate pathway activities.
• Nutritional Science: Applied in human and animal studies to investigate carbohydrate absorption, utilization, and energy expenditure.
• Biopharmaceutical Production: Can be used in media for cell culture processes to study nutrient consumption and optimize yield in the production of biologics.
• Biochemical Research: Acts as a substrate or standard in enzymatic assays and for the development of new diagnostic methods.

Basic Information

Product Name	D-Glucose-1,6-13C2
CAS No.	287100-67-8
Molecular Formula	C413C2H12O6
Molecular Weight	184.12 g/mol (for 13C2 labeled form)
Synonyms	1,6-13C2-D-Glucose; D-Glucose (1,6-13C2); [1,6-13C2]-D-Glucose; D-(+)-Glucose-1,6-13C2; Dextrose-1,6-13C2; 13C2-Labeled D-Glucose; (3R,4S,5S,6R)-6-(hydroxymethyl)oxane-2,3,4,5-tetrol-1,6-13C2; Glucose-1,6-13C2
EINECS	Contact for details

Quality Control

Every batch of D-Glucose-1,6-13C2 is produced and tested under strict quality management systems. We guarantee high chemical and isotopic purity, with specifications typically meeting or exceeding the requirements for research and diagnostic use. Comprehensive analytical data, including results from NMR, HPLC, and MS, are documented. Certificates of Analysis (COA) detailing assay, isotopic enrichment, and impurity profiles are provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive). For long-term stability, consider storage under an inert atmosphere in a desiccator.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Isotopic Enrichment (13C)	≥ 99 atom % 13C at positions 1 & 6
Specific Optical Rotation	+52.5° to +53.0° (c=10 in H2O)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.