Description

1-(4-Chloro-3-Methylphenyl)-2,2,2-Trifluoroethanol is a specialized fluorinated aromatic alcohol building block of significant interest in advanced chemical synthesis. Its unique structure, featuring both a chloro-methylphenyl group and a trifluoroethanol moiety, makes it a valuable intermediate for creating molecules with tailored properties. This compound is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries. It serves as a critical precursor in the development of active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly those requiring fluorinated motifs for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the trifluoromethyl group can improve biological activity and environmental profile.
• Liquid Crystal & OLED Material Precursor: Serves as a starting material for synthesizing fluorinated compounds used in electronic displays and organic light-emitting diodes.
• Advanced Polymer Monomer: Employed in the development of specialty polymers with unique solubility, surface energy, or chemical resistance properties.
• Organic Synthesis & Catalysis Research: A versatile reagent in academic and industrial research for constructing complex molecular architectures and exploring new catalytic transformations.
• Fluorine Chemistry Studies: Used as a model compound to study the effects of fluorine substitution on chemical reactivity and physical properties.

Basic Information

Product Name	1-(4-Chloro-3-Methylphenyl)-2,2,2-Trifluoroethanol
CAS No.	286017-73-0
Molecular Formula	C9H8ClF3O
Molecular Weight	224.61 g/mol
Synonyms	4-Chloro-3-methyl-α-(trifluoromethyl)benzenemethanol; 2,2,2-Trifluoro-1-(4-chloro-3-methylphenyl)ethanol; 1-(4-Chloro-3-methylphenyl)-2,2,2-trifluoroethan-1-ol; α-(Trifluoromethyl)-4-chloro-m-tolylmethanol; (4-Chloro-3-methylphenyl)(trifluoromethyl)methanol; p-Chloro-m-methyl-α-(trifluoromethyl)benzyl alcohol
EINECS	Contact for details

Quality Control

Our 1-(4-Chloro-3-Methylphenyl)-2,2,2-Trifluoroethanol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports applications requiring high-purity intermediates for research and cGMP-compliant production.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents, strong acids, and strong bases. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Purity (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.