Description

4-Chlorobenzaldehyde-α-13C is a stable isotope-labeled derivative of 4-chlorobenzaldehyde, where the carbonyl carbon is enriched with the carbon-13 isotope. This compound is essential as a high-purity internal standard and tracer in quantitative analytical chemistry, enabling precise measurement and method validation. It is primarily used by researchers and manufacturers in the pharmaceutical, agrochemical, and analytical reference material industries for advanced mass spectrometry (MS) and nuclear magnetic resonance (NMR) studies.

Application

• Internal Standard for Mass Spectrometry (MS): Critical for accurate quantification in LC-MS and GC-MS analysis of pharmaceuticals and metabolites.
• Metabolic Pathway Tracer: Used in biochemical and pharmacological research to track the fate of benzaldehyde derivatives in biological systems.
• NMR Spectroscopy Studies: Serves as a valuable probe for structural elucidation and reaction mechanism analysis due to the 13C label.
• Pharmaceutical Impurity Testing: Employed as a reference standard to identify and quantify impurities or degradation products in drug substances.
• Isotope Dilution Analysis: Enhances the accuracy and precision of analytical methods in environmental and food safety testing.
• Chemical Synthesis Intermediate: Used in the synthesis of more complex 13C-labeled compounds for research purposes.

Basic Information

Product Name	4-Chlorobenzaldehyde-α-13C
CAS No.	286013-17-0
Molecular Formula	C713CH5ClO
Molecular Weight	142.57 g/mol (for 13C labeled form)
Synonyms	p-Chlorobenzaldehyde-α-13C; 4-Chlorobenzenecarbonal-α-13C; (4-Chlorophenyl)formaldehyde-α-13C; 1-Chloro-4-formylbenzene-α-13C; p-Chloro-13C-benzaldehyde; 4-Cl-Ph-CHO-α-13C; Carbon-13 Labeled 4-Chlorobenzaldehyde
EINECS	Contact for details

Quality Control

Every batch of 4-Chlorobenzaldehyde-α-13C is produced and analyzed under strict quality management protocols to ensure exceptional isotopic and chemical purity, which is critical for its role as an analytical standard. We provide comprehensive Certificates of Analysis (COA) detailing isotopic enrichment (Atom % 13C), chemical purity by HPLC, and identification by NMR and IR spectroscopy. Our quality system supports compliance with cGMP and ISO standards for research and production materials.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is easily oxidized (store under inert atmosphere) and is light-sensitive (store away from light). For long-term storage under an inert atmosphere such as argon or nitrogen is recommended to maintain isotopic integrity and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Enrichment (Atom % 13C)	≥ 99%
Chemical Purity (by 1H NMR)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.