Description

2-Hydroxybenzoic Acid-D6 is a deuterated analog of salicylic acid, where six hydrogen atoms are replaced by the stable isotope deuterium. This compound is a critical internal standard and tracer in quantitative analytical chemistry, particularly for mass spectrometry (MS) and nuclear magnetic resonance (NMR) spectroscopy. It is essential for researchers and quality control laboratories in the pharmaceutical, agrochemical, and environmental science sectors who require high-purity isotopic labels for method development and accurate quantification.

Application

• Internal Standard for LC-MS/MS and GC-MS analysis of salicylic acid and related metabolites in pharmacokinetic studies.
• Isotopic Tracer in metabolic pathway research and degradation studies within plant biology and environmental science.
• Reference Material for the calibration and validation of analytical methods in pharmaceutical impurity profiling and bioanalysis.
• Deuterated Starting Material for the synthesis of more complex labeled compounds in medicinal chemistry and drug discovery.
• Quality Control in the manufacturing of deuterated active pharmaceutical ingredients (APIs) and fine chemicals.
• NMR Spectroscopy as a solvent or shift reference due to its distinct spectroscopic signature.

Basic Information

Product Name	2-Hydroxybenzoic Acid-D6
CAS No.	285979-87-5
Molecular Formula	C7D6O3
Molecular Weight	144.16 g/mol
Synonyms	Salicylic Acid-D6; Deuterated Salicylic Acid; 2-Hydroxy[2H6]benzoic Acid; [2H6]-Salicylic Acid; Benzoic-d6 Acid, 2-hydroxy-; (2,3,4,5,6-D5,COOH-D)Salicylic Acid; o-Hydroxybenzoic Acid-D6
EINECS	Contact for details

Quality Control

Our 2-Hydroxybenzoic Acid-D6 is manufactured under strict quality systems to ensure exceptional isotopic and chemical purity suitable for sensitive analytical applications. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing key parameters such as isotopic enrichment (Atom % D), chemical purity by HPLC, and identification by spectroscopic methods. We adhere to relevant industry guidelines for the production of stable isotope-labeled compounds.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); ensure the container is sealed after each use to minimize exposure to atmospheric humidity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 98.0%
Isotopic Enrichment (Atom % D)	≥ 98.0%
Chemical Purity (NMR)	Conforms
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.