Description

n-(Carboxymethyl)-N,N,n-Trimethyl-D9-Ammonium Chloride is a high-purity, deuterated analog of betaine hydrochloride, specifically designed for advanced research and analytical applications. This compound is valued for its role as a stable isotope-labeled internal standard in mass spectrometry, ensuring precise quantification and reliable analytical results. It is primarily utilized by researchers and quality control laboratories in the pharmaceutical, metabolomics, and biochemistry sectors for method development and validation.

Application

• Internal Standard for LC-MS/MS: Serves as a critical deuterated internal standard for the accurate quantification of betaine, choline, and related metabolites in complex biological matrices.
• Pharmaceutical Research: Used in pharmacokinetic and pharmacodynamic studies to track drug metabolism and ensure analytical method accuracy.
• Clinical Diagnostics: Supports the development of robust assays for measuring biomarkers related to cardiovascular health, liver function, and metabolic disorders.
• Nutraceutical Analysis: Essential for quality control and potency verification in betaine-containing dietary supplements and functional foods.
• Metabolomics & Systems Biology: Enables precise profiling of one-carbon metabolism pathways in research aimed at understanding disease mechanisms.
• Method Development & Validation: Provides a stable reference point for developing new analytical methods in compliance with regulatory guidelines (e.g., FDA, EMA).

Basic Information

Product Name	n-(Carboxymethyl)-N,N,n-Trimethyl-D9-Ammonium Chloride
CAS No.	285979-85-3
Molecular Formula	C6D9H5ClNO2
Molecular Weight	190.66 g/mol (for deuterated form)
Synonyms	Betaine-d9 Hydrochloride; (Carboxymethyl)trimethyl-d9-ammonium Chloride; Glycine Betaine-d9 HCl; N,N,N-Trimethylglycine-d9 Hydrochloride; 2-(Trimethyl-d9-ammonio)acetate Chloride; TMG-d9 HCl; Deuterated Betaine HCl; 285979-85-3
EINECS	Contact for details

Quality Control

Our n-(Carboxymethyl)-N,N,n-Trimethyl-D9-Ammonium Chloride is manufactured under strict quality systems to ensure exceptional isotopic purity and chemical integrity, suitable for sensitive analytical applications. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing parameters such as isotopic enrichment, chemical purity, and absence of critical impurities. We adhere to relevant standards for high-purity reference materials to support your compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation from atmospheric moisture. For long-term stability, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (Deuterium, D)	≥ 98 atom % D
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.