Description

Sodium L-Lactate-3,3,3-D3 is a high-purity, isotopically labeled derivative of sodium L-lactate, where three hydrogen atoms are replaced by deuterium at the 3-position. This compound is essential for advanced research and analytical applications requiring precise metabolic tracing and internal standards. It is primarily utilized by scientists and manufacturers in the pharmaceutical, biotechnology, and analytical chemistry sectors for applications such as NMR spectroscopy, mass spectrometry, and metabolic pathway studies.

Application

• Internal Standard for Mass Spectrometry (MS): Used for the accurate quantification of L-lactate in complex biological matrices via LC-MS or GC-MS.
• Metabolic Pathway Tracing: Serves as a deuterium-labeled tracer in in vitro and in vivo studies to investigate lactate metabolism, glycolysis, and gluconeogenesis.
• Nuclear Magnetic Resonance (NMR) Spectroscopy: Acts as a valuable probe in NMR studies due to the distinct signal of deuterium, aiding in structural and kinetic analyses.
• Pharmaceutical Research & Development: Employed in the development and validation of bioanalytical methods for drug metabolism and pharmacokinetics (DMPK) studies.
• Biochemical Research: Used in enzymatic assays and studies of lactate dehydrogenase (LDH) activity and regulation.
• Diagnostic Reagent Manufacturing: A key component in the production of calibrated reagents and kits for clinical diagnostics related to lactate levels.

Basic Information

Product Name	Sodium L-Lactate-3,3,3-D3
CAS No.	285979-84-2
Molecular Formula	C3H2D3NaO3
Molecular Weight	116.07 g/mol (approx.)
Synonyms	(2S)-2-Hydroxypropanoate-3,3,3-d3 sodium salt; Sodium (2S)-2-hydroxypropionate-3,3,3-d3; L-Lactic acid-3,3,3-d3 sodium salt; Deuterated sodium L-lactate; [3,3,3-2H3]-Sodium L-lactate; Sodium (S)-lactate-d3; Sodium 2-hydroxypropanoate-d3
EINECS	Contact for details

Quality Control

Our Sodium L-Lactate-3,3,3-D3 is manufactured under strict quality systems to ensure high isotopic and chemical purity, critical for research integrity. Each batch is characterized by advanced analytical techniques including NMR, MS, and HPLC. A comprehensive Certificate of Analysis (COA) detailing isotopic enrichment (typically >98 atom % D), chemical purity, and identity is provided with every shipment to support your compliance and documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent product degradation and ensure long-term stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Enrichment (NMR/MS)	≥ 98 atom % D
Chemical Purity (Titration)	≥ 97.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.