Description

(1S,2R)-(+)-Ephedrine-D3 Hcl (n-Methyl-D3) - Drug Precursor CAS NO 285979-73-9 is a high-purity, isotopically labeled derivative of ephedrine, specifically deuterated at the N-methyl position. This compound is of critical importance for use as an internal standard in quantitative analytical methods, ensuring accuracy and reliability in complex matrices. It is primarily required by pharmaceutical research and development laboratories, forensic science institutions, and analytical service providers engaged in method development, pharmacokinetic studies, and regulatory compliance testing.

Application

• Primary use as a deuterated internal standard for the precise quantification of ephedrine and related compounds via LC-MS/MS and GC-MS.
• Essential in pharmacokinetic and metabolic studies to track drug absorption, distribution, metabolism, and excretion (ADME).
• Critical for forensic analysis and doping control, providing definitive identification and measurement in biological samples.
• Supporting pharmaceutical R&D and quality control for method validation and impurity profiling.
• Used in the synthesis of other deuterium-labeled compounds for advanced research applications.
• Application in clinical research for patient sample analysis in therapeutic drug monitoring.

Basic Information

Product Name	(1S,2R)-(+)-Ephedrine-D3 Hcl (n-Methyl-D3) - Drug Precursor CAS NO 285979-73-9
CAS No.	285979-73-9
Molecular Formula	C10H12D3ClNO
Molecular Weight	203.72 g/mol
Synonyms	(+)-(1S,2R)-Ephedrine-d3 hydrochloride; (1S,2R)-Ephedrine-N-CD3 hydrochloride; [N-Methyl-d3]-Ephedrine hydrochloride; L-Ephedrine-d3 (N-methyl) HCl; 1R,2S-(-)-Ephedrine-d3 HCl (enantiomer); Erythro-2-(methylamino)-1-phenyl-1-propanol-d3 hydrochloride; 1-Phenyl-2-(methyl-d3-amino)-1-propanol hydrochloride; α-[1-(Methyl-d3-amino)ethyl]benzyl alcohol hydrochloride
EINECS	Contact for details

Quality Control

Our (1S,2R)-(+)-Ephedrine-D3 Hcl is manufactured under strict quality systems to ensure the high chemical and isotopic purity required for analytical standards. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing results for identity, assay, isotopic enrichment, and impurity profiles. We adhere to relevant industry guidelines for reference materials to support GMP and ISO 17025 compliant laboratories.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. This material is hygroscopic (moisture-sensitive); ensure containers are sealed tightly after use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Enrichment	≥ 98 atom % D
Chemical Purity (Titration)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Specific Rotation	+33° to +35° (c=2 in H2O)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.